Results 141 to 150 of about 457,033 (338)

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

Angewandte Chemie, EarlyView.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito, Yoshiyuki Manabe, Shino Ohshima, Masatoshi Maeki, Manabu Tokeshi, Hiroshi Inaba, Kazunori Matsuura, Kazuya Kabayama, Yoshie Kametani, Koichi Fukase   +9 more
wiley   +2 more sources

Probing the Intergalactic Medium with Ly$\mathrm{\alpha}$ and 21 cm Fluctuations

, 2017
We study 21cm and Ly$\mathrm{\alpha}$ fluctuations, as well as H$\mathrm{\alpha}$, while distinguishing between Ly$\mathrm{\alpha}$ emission of galactic, diffuse, and scattered intergalactic medium (IGM) origin.
Cooray, Asantha, Feng, Chang, Heneka, Caroline   +2 more
core   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites

, 2021
Christopher D. Thouvenel, Mary F. Fontana, Jason Netland, Akshay T. Krishnamurty, Kennidy K. Takehara, Yu Chen, Suruchi Singh, Kazutoyo Miura, Gladys J. Keitany, Eric M. Lynch, Sílvia Portugal, Marcos C. Miranda, Neil P. King, Justin M. Kollman, Peter D. Crompton, Carole A. Long, Marie Pancera, David J. Rawlings, Marion Pepper   +18 more
openalex   +1 more source

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic intestinal inflammation and impaired barrier function, for which effective long‐term therapies remain elusive. To address this challenge, we developed a novel nano‐vaccine that combines Prussian blue nanozymes (PBNZs) adjuvants with a ferritin carrier loaded with ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

Study of Serum IgM, IgG, IL-37 Levels and IL-37 Gene Polymorphism in Women Infected with Trichomonas Vaginalis in Baqubah City

Proceedings of the International Conference on Applied Innovations in IT
Trichomoniasis is the most prevalent non-viral sexually transmitted infection globally, relying on both innate and adaptive immunity to combat the extracellular pathogen Trichomonas vaginalis. This study included 45 infected women and 45 healthy controls
Noor Ghassan, Maha Falih Nazzal, Ibtisam Badday Hassan   +2 more
doaj   +1 more source

Age-Related Decline in Natural IgM Function: Diversification and Selection of the B-1a Cell Pool with Age [PDF]

, 2016
Nichol E. Holodick, Teresa Vizconde, Thomas J Hopkins, Thomas L. Rothstein   +3 more
openalex   +1 more source

AI‐Assisted Bioelectronics for Personalized Health Management

Advanced Electronic Materials, EarlyView.
Recent advances in artificial intelligence (AI)‐assisted bioelectronics, including materials, device fabrication, working mechanisms, AI‐hardware integration, and proof‐of‐concept applications in digital health management, are summarized. The emergence of AI‐assisted bioelectronic systems and potential solutions to existing challenges are discussed ...
Huiwen Xiong, Changhao Dai, Xuting Chen, Jilie Kong, Dacheng Wei, Xueen Fang, Wenhao Weng   +6 more
wiley   +1 more source

DESCRIPTION OF CUSTOM THREAD IGM TECHNIQUE WITH USE OF PDO FACIAL SUPPORT THREADS IN THE OROFACIAL HARMONIZATION.

, 2021
Gustavo Otoboni Molina, Joze Fabiana Garcia Molina, Sheila Soratto Zeferino Nandi, Eduarda Braz   +3 more
openalex   +1 more source

Nance‐Horan Syndrome: Further Delineation of the Affected Male and the Female Carrier Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nance‐Horan syndrome (NHS; OMIM 302350) is a rare, X‐linked syndrome characterized by bilateral congenital cataracts leading to profound vision loss, specific dental anomalies including characteristic screwdriver blade‐shaped incisors, facial anomalies, and intellectual disability.
Maria K. Haanpää, Chad R. Haldeman‐Englert, Marja Hietala, Melisa S. Tanverdi, Patrick P. Koty, Diana Brightman, Eniolami Dosunmu, Shailja Tibrewal, Savleen Kaur, Anupriya Kaur, Raj Kumar Verma, Alejandra G. de Alba Campomanes, Virginia Utz, Anne M. Slavotinek, Cynthia Curry   +14 more
wiley   +1 more source