Results 161 to 168 of about 4,347 (168)

COP II-mediated ER-to-Golgi transport is a bottleneck for IgNAR-Fc production in the Chinese hamster ovary cell expression system

Journal of Bioscience and Bioengineering
The novel heavy-chain antibody known as immunoglobulin new antigen receptor (IgNAR) is derived from cartilaginous fishes such as sharks. IgNAR, which binds to antigens with the high specificity and affinity of a conventional IgG antibody and exhibits high resistance to denaturation, has potential as a next-generation antibody in biopharmaceutical and ...
Yuichi Koga, Noriko Yamano, Takeshi Omasa   +2 more
exaly   +3 more sources

IgNAR

2008
openaire   +1 more source

Structural insights and biomedical potential of IgNAR scaffolds from sharks

MAbs, 2015
Stefan Zielonka, Martin Empting, Caroline J Barelle   +2 more
exaly  

Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): identification of a new locus preferentially expressed in early development

Immunogenetics, 2002
Marilyn Diaz, Andrew S Greenberg, Martin F Flajnik   +2 more
exaly  

Structure and Function of IgNARS in Sharks and Other Cartilaginous Fish

2016
openaire   +1 more source

Characteristics and Genomic Localization of Nurse Shark (Ginglymostoma cirratum) IgNAR

International Journal of Molecular Sciences
Xiaofeng Jiang, Guodong Chen
exaly  

Des ignares qui s’ignorent

openaire   +1 more source

Establishment and Application of a Method for the Detection of Single-Domain Ignar Antibody Levels in Chiloscyllium Plagiosum

Yangying LONG, Xiaofeng JIANG, Feijian ZHENG, Jianqing CHEN, Zhengbing LYV   +4 more
openaire   +1 more source