Basics of Antibody Phage Display Technology
Toxins, 2018 Antibody discovery has become increasingly important in almost all areas of modern medicine. Different antibody discovery approaches exist, but one that has gained increasing interest in the field of toxinology and antivenom research is phage display ...
Line Ledsgaard +4 more
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A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides [PDF]
VirusesPhage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs).
Babak Bakhshinejad, Saeedeh Ghiasvand
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Oligopeptide M13 Phage Display in Pathogen Research
Viruses, 2013 Phage display has become an established, widely used method for selection of peptides, antibodies or alternative scaffolds. The use of phage display for the selection of antigens from genomic or cDNA libraries of pathogens which is an alternative to the ...
Michael Hust +3 more
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On the origin of non-specific binders isolated in the selection of phage display peptide libraries [PDF]
Frontiers in MicrobiologyOver the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of ...
Babak Bakhshinejad +3 more
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Using NGS to Uncover the Corruption of a Peptide Phage Display Selection [PDF]
Current Issues in Molecular BiologyPhage display has been widely used to identify peptides binding to a variety of biological targets. In the current work, we planned to select novel peptides targeting CD4 through screening of a commercial phage display library (New England Biolabs Ph.D ...
Danna Kamstrup Sell +7 more
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NGS and the design of an optimized phage display workflow for peptide discovery [PDF]
Amino AcidsPhage display is a powerful technology that has demonstrated great potential in identifying peptides with high binding affinity and specificity toward a broad spectrum of biological targets. The undesired enrichment of nonspecific binders remains a major
Babak Bakhshinejad, Andreas Kjaer
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Development of an Anti-Zearalenone Nanobody Phage Display Library and Preparation of Specific Nanobodies [PDF]
Current Issues in Molecular BiologyZearalenone (ZEN), a toxic estrogenic mycotoxin in cereals, threatens human and animal health through reproductive, immune, and cytotoxic effects, necessitating sensitive detection methods.
Ying Zeng +9 more
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Phage display technology in ecotoxicology: phage display derived unique peptide for copper identification in aquatic samples [PDF]
Microbial Cell FactoriesBackground Ecotoxicology is essential for the evaluation and comprehension of the effects of emergency pollutants (EP) such as heavy metal ions on the natural environment.
Marta Sosnowska +3 more
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Evolution of phage display libraries for therapeutic antibody discovery
mAbs, 2023 Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most important classes of biotherapeutics in recent decades. The success of mAb is due to their high versatility, high target specificity, excellent clinical safety profile ...
Yang Zhang
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Phage Display Informatics [PDF]
Computational and Mathematical Methods in Medicine, 2013 Phage display is an efficient laboratory technique that can be used to screen for specific peptides and proteins displayed on the surface of bacteriophage. Since Professor George Smith of the University of Missouri pioneered the powerful and flexible method in 1980s [1], it has been adapted and improved by many scientists from various fields.
Jian Huang 0004 +2 more
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