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Basics of Antibody Phage Display Technology [PDF]
Toxins, 2018 Antibody discovery has become increasingly important in almost all areas of modern medicine. Different antibody discovery approaches exist, but one that has gained increasing interest in the field of toxinology and antivenom research is phage display ...
Line Ledsgaard +2 more
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Oligopeptide M13 Phage Display in Pathogen Research
Viruses, 2013 Phage display has become an established, widely used method for selection of peptides, antibodies or alternative scaffolds. The use of phage display for the selection of antigens from genomic or cDNA libraries of pathogens which is an alternative to the ...
Jonas Kugler +2 more
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Evolution of phage display libraries for therapeutic antibody discovery
mAbs, 2023 Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most important classes of biotherapeutics in recent decades. The success of mAb is due to their high versatility, high target specificity, excellent clinical safety profile ...
Yang Zhang
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Frontiers in Microbiology, 2022 The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody research and clinical development.
Ana S. André +7 more
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Landscape Phage: Evolution from Phage Display to Nanobiotechnology
Viruses, 2018 The development of phage engineering technology has led to the construction of a novel type of phage display library—a collection of nanofiber materials with diverse molecular landscapes accommodated on the surface of phage particles.
Valery A. Petrenko
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Phage display screening of therapeutic peptide for cancer targeting and therapy
Protein & Cell, 2019 Recently, phage display technology has been announced as the recipient of Nobel Prize in Chemistry 2018. Phage display technique allows high affinity target-binding peptides to be selected from a complex mixture pool of billions of displayed peptides on ...
Phei Er Saw, Er-Wei Song
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A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides [PDF]
VirusesPhage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs).
Babak Bakhshinejad, Saeedeh Ghiasvand
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An overview on application of phage display technique in immunological studies
Asian Pacific Journal of Tropical Biomedicine, 2017 Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami +4 more
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International Journal of Nanomedicine, 2015 Kaushik Rajaram,1 Patricia Losada-Pérez,2,3 Veronique Vermeeren,1 Baharak Hosseinkhani,1 Patrick Wagner,2,4 Veerle Somers,1 Luc Michiels1 1Biomedical Research Institute (BIOMED), Hasselt University, Hasselt, 2Institute for Materials Research (IMO)
Rajaram K +6 more
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On the origin of non-specific binders isolated in the selection of phage display peptide libraries [PDF]
Frontiers in MicrobiologyOver the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of ...
Babak Bakhshinejad +3 more
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