Results 1 to 10 of about 63,473 (252)

Basics of Antibody Phage Display Technology

open access: yesToxins, 2018
Antibody discovery has become increasingly important in almost all areas of modern medicine. Different antibody discovery approaches exist, but one that has gained increasing interest in the field of toxinology and antivenom research is phage display ...
Andreas Hougaard Laustsen   +2 more
exaly   +3 more sources

Landscape Phage: Evolution from Phage Display to Nanobiotechnology

open access: yesViruses, 2018
The development of phage engineering technology has led to the construction of a novel type of phage display library—a collection of nanofiber materials with diverse molecular landscapes accommodated on the surface of phage particles.
Valery Petrenko, Petrenko Valery A
exaly   +3 more sources

Oligopeptide M13 Phage Display in Pathogen Research

open access: yesViruses, 2013
Phage display has become an established, widely used method for selection of peptides, antibodies or alternative scaffolds. The use of phage display for the selection of antigens from genomic or cDNA libraries of pathogens which is an alternative to the ...
Michael Hust   +2 more
exaly   +3 more sources

A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides [PDF]

open access: yesViruses
Phage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs).
Babak Bakhshinejad, Saeedeh Ghiasvand
doaj   +2 more sources

On the origin of non-specific binders isolated in the selection of phage display peptide libraries [PDF]

open access: yesFrontiers in Microbiology
Over the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of ...
Babak Bakhshinejad   +3 more
doaj   +2 more sources

NGS and the design of an optimized phage display workflow for peptide discovery [PDF]

open access: yesAmino Acids
Phage display is a powerful technology that has demonstrated great potential in identifying peptides with high binding affinity and specificity toward a broad spectrum of biological targets. The undesired enrichment of nonspecific binders remains a major
Babak Bakhshinejad, Andreas Kjaer
doaj   +2 more sources

Development of an Anti-Zearalenone Nanobody Phage Display Library and Preparation of Specific Nanobodies [PDF]

open access: yesCurrent Issues in Molecular Biology
Zearalenone (ZEN), a toxic estrogenic mycotoxin in cereals, threatens human and animal health through reproductive, immune, and cytotoxic effects, necessitating sensitive detection methods.
Ying Zeng   +9 more
doaj   +2 more sources

Phage display technology in ecotoxicology: phage display derived unique peptide for copper identification in aquatic samples [PDF]

open access: yesMicrobial Cell Factories
Background Ecotoxicology is essential for the evaluation and comprehension of the effects of emergency pollutants (EP) such as heavy metal ions on the natural environment.
Marta Sosnowska   +3 more
doaj   +2 more sources

Evolution of phage display libraries for therapeutic antibody discovery

open access: yesmAbs, 2023
Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most important classes of biotherapeutics in recent decades. The success of mAb is due to their high versatility, high target specificity, excellent clinical safety profile ...
Yang Zhang
doaj   +1 more source

Determination of the affinity constants for phage display albumin-binding peptides [PDF]

open access: yesPeerJ, 2023
Background Phage display technology has been established as a powerful screening approach to select ligands or peptides for binding to proteins. Despite rapid growth in the field, there has been a relative dearth of quantitative criteria to measure the ...
Yi-Feng Shi
doaj   +2 more sources

Home - About - Disclaimer - Privacy