Results 31 to 40 of about 978,488 (287)
Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. [PDF]
PLoS ONE, 2013 In this work, we exploited a method that uses polytopic membrane proteins as targets for phage display selections. Membrane proteins represent the largest class of drug targets and drug discovery is mostly based on the identification of ligands binding ...
Marina Pavlidou +3 more
doaj +1 more source
Construction of Synthetic Antibody Phage-Display Libraries
, 2017 Synthetic antibody libraries provide a vast resource of renewable antibody reagents that can rival or exceed those of natural antibodies and can be rapidly isolated through controlled in vitro selections.
Nilvebrant, Johan, +3 more
core +1 more source
Feeling Loki's Pain: Designing and Evaluating a DIY 3D Auditory Display for Geodata Sonification
, 2021 Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.Loki's Pain is an ...
Lindborg, PerMagnus, PerMagnus Lindborg
core +1 more source
, 2008 (Abstract) Phage display is emerging as a promising strategy for the discovery of peptide ligands that are used for analytical tools, drug discovery, and target validations.
244 +5 more
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Phage display technology: applications and innovations
Genetics and Molecular Biology, 2005 The expression of exogenous peptides on the surface of filamentous bacteriophage was initially described by Smith in 1985. Since his first study, different molecules such as small peptides and antibodies have been displayed on coat proteins of phage ...
Marco Antonio Arap
doaj +1 more source
Modulation of antibody display on M13 filamentous phage
, 1998 Here we describe a phage vector for the display of single chain antibodies and polypeptides on the surface of filamentous M13 phage which permits facile manipulation of the valency of display.
Kang, A.S., He, M., Chappel, J.A.
core +1 more source
To sonify or not to sonify? Educator perceptions of auditory display in interactive simulations
, 2021 Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.With the growing ...
Walker, Bruce N. +2 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source