Results 21 to 30 of about 73,738 (335)

Phage Display Technique as a Tool for Diagnosis and Antibody Selection for Coronaviruses

Current Microbiology, 2021
Phage display is one of the important and effective molecular biology techniques and has remained indispensable for research community since its discovery in the year 1985.
T. Anand, N. Virmani, B. C. Bera, R. Vaid, M. Vashisth, Priyanka Bardajatya, Ashok Kumar, B. N. Tripathi   +7 more
semanticscholar   +1 more source

Phage Display Technology as a Powerful Platform for Antibody Drug Discovery

Viruses, 2021
Antibody drugs with a high affinity and specificity are effective and safe for intractable diseases, such as cancers and autoimmune diseases. Furthermore, they have played a central role in drug discovery, currently accounting for eight of the top 20 ...
K. Nagano, Y. Tsutsumi
semanticscholar   +1 more source

Determination of the affinity constants for phage display albumin-binding peptides [PDF]

PeerJ, 2023
Background Phage display technology has been established as a powerful screening approach to select ligands or peptides for binding to proteins. Despite rapid growth in the field, there has been a relative dearth of quantitative criteria to measure the ...
Yi-Feng Shi
doaj   +2 more sources

SpyDisplay: A versatile phage display selection system using SpyTag/SpyCatcher technology

mAbs, 2023
Phage display is an established method for the in vitro selection of recombinant antibodies and other proteins or peptides from gene libraries. Here we describe SpyDisplay, a phage display method in which the display is achieved via SpyTag/SpyCatcher ...
Sarah-Jane Kellmann, Christian Hentrich, Mateusz Putyrski, Hanh Hanuschka, Manuel Cavada, Achim Knappik, Francisco Ylera   +6 more
doaj   +1 more source

The Biotechnological Application of Bacteriophages: What to Do and Where to Go in the Middle of the Post-Antibiotic Era

Microorganisms, 2023
Amid the escalating challenges of antibiotic resistance, bacterial infections have emerged as a global threat. Bacteriophages (phages), viral entities capable of selectively infecting bacteria, are gaining momentum as promising alternatives to ...
Su Jin Jo, Jun Kwon, Sang Guen Kim, Seung-Jun Lee   +3 more
doaj   +1 more source

Advancement in the development of single chain antibodies using phage display technology [PDF]

PeerJ
Phage display technology has become an important research tool in biological research, fundamentally changing the traditional monoclonal antibody preparation process, and has been widely used in the establishment of antigen-antibody libraries, drug ...
Xiaohui Zheng, Qi Liu, Yimin Liang, Wenzhi Feng, Honghao Yu, Chunyu Tong, Bocui Song   +6 more
doaj   +2 more sources

Phage display: Binding confirmation

BioTechniques, 2010
This month's question from the Molecular Biology Forums (online at molecularbiology.forums.biotechniques.com) comes from the “Protein Methods” section. Entries have been edited for concision and clarity.
Kristie Nybo
doaj   +1 more source

Phage Display Derived Monoclonal Antibodies: From Bench to Bedside

Frontiers in Immunology, 2020
Monoclonal antibodies (mAbs) have become one of the most important classes of biopharmaceutical products, and they continue to dominate the universe of biopharmaceutical markets in terms of approval and sales.
M. Alfaleh, H. Alsaab, A. Mahmoud, A. Alkayyal, Martina L. Jones, S. Mahler, A. Hashem   +6 more
semanticscholar   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Camacho, F., Perez, E.M., Amin, N., Aguilar, A., David I. Stott, Talavera, A., Arturo Talavera, Raiza Martinez, Frank Camacho, Nevis Amin, Ela M. Perez, Larralde, O.G., Alicia Aguilar, Martinez, R., Osmany G. Larralde, Stott, D.I.   +15 more
core   +1 more source

Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis [PDF]

, 2015
Adhirons are robust, well expressing, peptide display scaffold proteins, developed as an effective alternative to traditional antibody binding proteins for highly specific molecular recognition applications.
Bramble, Jonathan P., McPherson, M.J., Rawlings, AE, Tang, AAS, Cooke, David J., Somner, LA, McPherson, Michael J., Tomlinson, Darren C., Staniland, S.S., Monnington, AE, Staniland, Sarah S., Tang, A.A.S., McPherson, MJ, Bramble, J.P., Tomlinson, DC, Somner, L.A., Somner, Lori A., Cooke, DJ, Monnington, A.E., Staniland, SS, Rawlings, Andrea E., Bramble, JP, Cooke, D.J., Tang, Anna A. S., Monnington, Amy E., Tomlinson, D.C., Rawlings, A.E.   +26 more
core   +1 more source