Results 21 to 30 of about 114,213 (298)
Landscape Phage: Evolution from Phage Display to Nanobiotechnology
Viruses, 2018 The development of phage engineering technology has led to the construction of a novel type of phage display library—a collection of nanofiber materials with diverse molecular landscapes accommodated on the surface of phage particles.
Valery A. Petrenko
doaj +1 more source
Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]
, 2012 UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles +13 more
core +2 more sources
Microbiology Spectrum, 2015 ABSTRACT Despite the availability of antimicrobial drugs, the continued development of microbial resistance—established through escape mutations and the emergence of resistant strains—limits their clinical utility. The discovery of novel, therapeutic, monoclonal antibodies (mAbs) offers viable clinical alternatives in the ...
Jared, Sheehan, Wayne A, Marasco
openaire +2 more sources
An overview on application of phage display technique in immunological studies
Asian Pacific Journal of Tropical Biomedicine, 2017 Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami +4 more
doaj +1 more source
Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites [PDF]
, 2012 The vast majority of anti-infective therapeutics on the market or in development are small molecules; however, there is now a nascent pipeline of biological agents in development.
Bishop-Hurley, Sharon L. +2 more
core +1 more source
Identification of Calpain Substrates by ORF Phage Display
Molecules, 2011 Substrate identification is the key to defining molecular pathways or cellular processes regulated by proteases. Although phage display with random peptide libraries has been used to analyze substrate specificity of proteases, it is difficult to deduce ...
Wei Li +2 more
doaj +1 more source
A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. [PDF]
, 2013 Bacteriophage BPP-1 infects and kills Bordetella species that cause whooping cough. Its diversity-generating retroelement (DGR) provides a naturally occurring phage-display system, but engineering efforts are hampered without atomic structures.
Czornyj, Elizabeth +8 more
core +1 more source
Molecules, 2021 Mycotoxins, the small size secondary metabolites of fungi, have posed a threat to the safety of medicine, food and public health. Therefore, it is essential to create sensitive and effective determination of mycotoxins.
Wei Sun, Yan Zhang, Zhigang Ju
doaj +1 more source
Detection of hepatitis B virus core antigen by phage display mediated TaqMan real-time immuno-PCR [PDF]
, 2013 The core antigen (HBcAg) of hepatitis B virus (HBV) is one of the markers for the identification of the viral infection. The main purpose of this study was to develop a TaqMan real-time detection assay based on the concept of phage display mediated ...
Monjezi, Razieh +4 more
core +1 more source
Frameshifting in the P6 cDNA Phage Display System
Molecules, 2010 Phage display is a powerful technique that enables easy identification of targets for any type of ligand. Targets are displayed at the phage surface as a fusion protein to one of the phage coat proteins.
Veerle Somers +3 more
doaj +1 more source