Results 11 to 20 of about 73,738 (335)
Phage Display-Based Nanotechnology Applications in Cancer Immunotherapy
Molecules, 2020 Phage display is a nanotechnology with limitless potential, first developed in 1985 and still awaiting to reach its peak. Awarded in 2018 with the Nobel Prize for Chemistry, the method allows the isolation of high-affinity ligands for diverse substrates,
Martina Goracci +2 more
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Phage Display Libraries for Antibody Therapeutic Discovery and Development
Antibodies, 2019 Phage display technology has played a key role in the remarkable progress of discovering and optimizing antibodies for diverse applications, particularly antibody-based drugs.
Juan C. Almagro +3 more
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NGS and the design of an optimized phage display workflow for peptide discovery [PDF]
Amino AcidsPhage display is a powerful technology that has demonstrated great potential in identifying peptides with high binding affinity and specificity toward a broad spectrum of biological targets. The undesired enrichment of nonspecific binders remains a major
Babak Bakhshinejad, Andreas Kjaer
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Eliminating helper phage from phage display [PDF]
Nucleic Acids Research, 2006 Phage display technology involves the display of proteins or peptides, as coat protein fusions, on the surface of a phage or phagemid particles. Using standard technology, helper phage are essential for the replication and assembly of phagemid particles, during library production and biopanning. We have eliminated the need to add helper phage by using '
Chasteen, L. +3 more
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Nanoscale bacteriophage biosensors beyond phage display
International Journal of Nanomedicine, 2013 Jong-Wook Lee,1 Jangwon Song,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea; 2Department of Biomedical Engineering, University of Science and ...
Lee JW, Song J, Hwang MP, Lee KH
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Phage display technology in ecotoxicology: phage display derived unique peptide for copper identification in aquatic samples [PDF]
Microbial Cell FactoriesBackground Ecotoxicology is essential for the evaluation and comprehension of the effects of emergency pollutants (EP) such as heavy metal ions on the natural environment.
Marta Sosnowska +3 more
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Phage display derived peptides for Alzheimer's disease therapy and diagnosis
Theranostics, 2022 Alzheimer's disease (AD) is an incurable and fatal progressive neurodegenerative disorder associated with memory and cognition impairment. AD is one of the top medical care concerns across the world with a projected economic burden of $2 trillion by 2030.
Xiancheng Zhang +3 more
semanticscholar +1 more source
Lysine-Targeted Reversible Covalent Ligand Discovery for Proteins via Phage Display
Journal of the American Chemical Society, 2022 Binding via reversible covalent bond formation presents a novel and powerful mechanism to enhance the potency of synthetic inhibitors for therapeutically important proteins.
Mengmeng Zheng +5 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Antibodies are essential molecules for diagnosis and treatment of diseases caused by pathogens and their toxins. Antibodies were integrated in our medical repertoire against infectious diseases more than hundred years ago by using animal sera to treat ...
K. Roth +17 more
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Phage Display Informatics [PDF]
Computational and Mathematical Methods in Medicine, 2013 Phage display is an efficient laboratory technique that can be used to screen for specific peptides and proteins displayed on the surface of bacteriophage. Since Professor George Smith of the University of Missouri pioneered the powerful and flexible method in 1980s [1], it has been adapted and improved by many scientists from various fields.
Jian Huang 0004 +2 more
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