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Phage Display Informatics [PDF]
Computational and Mathematical Methods in Medicine, 2013 Phage display is an efficient laboratory technique that can be used to screen for specific peptides and proteins displayed on the surface of bacteriophage. Since Professor George Smith of the University of Missouri pioneered the powerful and flexible method in 1980s [1], it has been adapted and improved by many scientists from various fields.
Jian Huang 0004 +2 more
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SpyDisplay: A versatile phage display selection system using SpyTag/SpyCatcher technology
mAbs, 2023 Phage display is an established method for the in vitro selection of recombinant antibodies and other proteins or peptides from gene libraries. Here we describe SpyDisplay, a phage display method in which the display is achieved via SpyTag/SpyCatcher ...
Sarah-Jane Kellmann +6 more
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Microorganisms, 2023 Amid the escalating challenges of antibiotic resistance, bacterial infections have emerged as a global threat. Bacteriophages (phages), viral entities capable of selectively infecting bacteria, are gaining momentum as promising alternatives to ...
Su Jin Jo +3 more
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Advancement in the development of single chain antibodies using phage display technology [PDF]
PeerJPhage display technology has become an important research tool in biological research, fundamentally changing the traditional monoclonal antibody preparation process, and has been widely used in the establishment of antigen-antibody libraries, drug ...
Xiaohui Zheng +6 more
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Phage display: Binding confirmation
BioTechniques, 2010 This month's question from the Molecular Biology Forums (online at molecularbiology.forums.biotechniques.com) comes from the “Protein Methods” section. Entries have been edited for concision and clarity.
Kristie Nybo
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Frontiers in Microbiology, 2022 The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody research and clinical development.
Ana S. André +7 more
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Microbiology Spectrum, 2015 ABSTRACT Despite the availability of antimicrobial drugs, the continued development of microbial resistance—established through escape mutations and the emergence of resistant strains—limits their clinical utility. The discovery of novel, therapeutic, monoclonal antibodies (mAbs) offers viable clinical alternatives in the ...
Jared, Sheehan, Wayne A, Marasco
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An overview on application of phage display technique in immunological studies
Asian Pacific Journal of Tropical Biomedicine, 2017 Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami +4 more
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Identification of Calpain Substrates by ORF Phage Display
Molecules, 2011 Substrate identification is the key to defining molecular pathways or cellular processes regulated by proteases. Although phage display with random peptide libraries has been used to analyze substrate specificity of proteases, it is difficult to deduce ...
Wei Li +2 more
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Frameshifting in the P6 cDNA Phage Display System
Molecules, 2010 Phage display is a powerful technique that enables easy identification of targets for any type of ligand. Targets are displayed at the phage surface as a fusion protein to one of the phage coat proteins.
Veerle Somers +3 more
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