Results 151 to 160 of about 1,058,742 (271)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Optimum design of composite laminates with thermal effects [PDF]
An analytical approach to determine an optimum laminate for a variety of thermal and mechanical loading combinations is presented. The analysis is performed for a linear elastic material under static mechanical and uniform thermal loadings.
Herakovich, C. T., Markham, L. R.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2018 Serum levels of interleukin (IL)-33, IL-36 and IL-37 have been reported to be up-regulated in various T helper (Th)1/Th17 mediated autoimmune/inflammatory diseases.
Mojtaba Sehat +4 more
doaj
New insights on IL‑36 in intestinal inflammation and colorectal cancer (Review). [PDF]
Exp Ther Med, 2023 Li M, Jiang W, Wang Z, Lu Y, Zhang J.
europepmc +1 more source
TNT equivalency of M10 propellant [PDF]
Peak, side-on blast overpressure and scaled, positive impulse have been measured for M10 single-perforated propellant, web size 0.018 inches, using configurations that simulate the handling of bulk material during processing and shipment.
Mcintyre, F. L., Price, P.
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Social Preferences - Literature Survey [PDF]
This paper surveys the theories of social preferences. Social preferences are based on that people not only care about their own well-being, but they have a certain concern with payoffs and/or actions of others. We classify two approaches: distributional
Kovarik, Jaromir
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source