Results 231 to 240 of about 1,058,742 (271)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

New and Emerging Treatments for Generalized Pustular Psoriasis: Focus on IL-36 Receptor Inhibitors. [PDF]

Pharmaceutics
Vilaça J, Yilmaz O, Torres T.
europepmc   +1 more source

Concorso pubblico, per il reclutamento di 3.839 unità da assumere con rapporti di lavoro a tempo pieno e determinato, per una durata non superiore a 36 mesi, presso gli Ambiti Territoriali Sociali - Nazionale - Ministero del Lavoro e delle Politiche Sociali

Easy Quizzz
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Dual blockade of IL-17A and IL-36 pathways via a bispecific antibody exhibits enhanced anti-inflammatory potency. [PDF]

Front Immunol
Ma X, Zhang S, Ren X, Feng Y, Li H, Chen S, Xu J, Wang Y, Peng GY, Yan Q, Jia H, Xia S, Cui X, Chen X, Pan X, Wang S, Yu H, Wei X, Li M, Liu B, Xu J, Qian Q, Zhu X, Zhan Y, Lu L.   +24 more
europepmc   +1 more source

IL-36 Signaling in the Tumor Microenvironment. [PDF]

Adv Exp Med Biol, 2020
Chelvanambi M, Weinstein AM, Storkus WJ.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Endothelial IL-36 receptor activation promotes vascular stability to limit pathological microvessel permeability in the CNS.

Cell Rep
Fahey E, Celkova L, Frezza V, Sullivan GP, Byrne K, Watson A, Hernandez-Santana YE, Byrne K, Dalton R, Efe-Cicek H, O'Callaghan J, Delaney C, Ozaki E, Walsh PT, Martin SJ, Campbell M, Doyle SL.   +16 more
europepmc   +1 more source

Successful Treatment of Pediatric Generalized Pustular Psoriasis (GPP) with Spesolimab: 5 Case Reports and Evaluations of Circulating IL-36 Levels. [PDF]

J Inflamm Res
Chen Y, Wang Z, Liang Y, Shen C, Jiao L, Xiang X, Miao C, Xu Z.   +7 more
europepmc   +1 more source

Participación de la familia de la IL-36 en las enfermedades metabólicas

Nicté Guadalupe Figueroa-Vega, Mayra Ivette Martínez de la Cruz, Ruth Elena Torres Díaz, Adriana Anabel Aguilera Guevara, F. Hernández, Ximena Ávalos Ayala   +5 more
openalex   +2 more sources