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Statins Regulate IL-1β - Induced RANKL and OPG Production by Human Gingival Fibroblasts

2018
Three-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase competitive inhibitors, also known as statins, are widely used agents for lowering cholesterol and reducing the risk for a heart attack. Recent data suggest that statins influence bone metabolic activity by stimulating new bone formation both in vivo and in vitro. Bone resorption in periodontitis,
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Interleukin-1 Beta (IL-1_) Gene Polymorphisms in Pre-Treatment Orthodontic Patients Exhibiting Short Root Anomaly (SRA)

2018
Root resorption is a frequent unwanted occurrence during orthodontic treatment. Biological factors include the quantity of specific inflammatory mediators, growth factors, and hormones as well as an individual's specific alleles for the genes encoding these mediators.
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