Results 311 to 320 of about 2,610,317 (379)

IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization

Nature Cell Biology, 2018
Z. Castaño, Beatriz P. San Juan, Asaf Spiegel, Ayush Pant, Molly J Decristo, Tyler Laszewski, Jessalyn M. Ubellacker, S. Janssen, Anushka Dongre, Ferenc Reinhardt, Ayana L. Henderson, Ana García del Río, A. Gifford, Zachary T. Herbert, John N. Hutchinson, R. Weinberg, Christine L. Chaffer, S. McAllister   +17 more
semanticscholar   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Macrophage NLRP3 activation and IL-1β release drive osimertinib-induced antitumor immunity. [PDF]

J Immunother Cancer
Yu H, Sun X, Li Y, Pan J, Liu X, He H, Wu H, Sun Y, Pan Y, Qian X.   +9 more
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Prognostic Value of FasL, BDNF, and IL-1β as Predictors of Therapeutic Response in Schizophrenia. [PDF]

J Clin Med
Szymona-Kuciewicz Z, Owe-Larsson M, Flis M, Karakula-Juchnowicz H, Zdzisinska B, Dudzinska E, Urbanska EM, Szymona K.   +7 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

IL-1β Controls Proliferation, Apoptosis, and Necroptosis Through the PI3K/AKT/Src/NF-κB Pathway in Leukaemic Lymphoblasts. [PDF]

Biomedicines
Victoria-Avila ZL, Reyes-Maldonado E, Domínguez-López ML, Vela-Ojeda J, Lozada-Ruiz A, Alemán OR, Lezama RA.   +6 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Academic stress through salivary biomarkers: A multivariate exploration of cortisol, IL-1β, CRP, and IgA levels with sex-specific insights. [PDF]

PLoS One
Castillo-Klagges R, Pezo-Sáez C, Aguila L, Pantoja V, Treulen F.   +4 more
europepmc   +1 more source

IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects

, 2017
Ivana Machado, Helgi B. Schiöth, Mercedes Lasaga, Teresa Scimonelli   +3 more
openalex   +2 more sources