Results 191 to 200 of about 15,170,590 (380)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Relationship Between IL-10 Gene Polymorphism and Spinal Tuberculosis
, 2019 Jinming Ma +3 more
openalex +2 more sources
Increased expression of IL-10 and IL-12 (p40) mRNA in Helicobacter pylori infected gastric mucosa: relation to bacterial cag status and peptic ulceration. [PDF]
, 1999 Nobuyuki Hida +6 more
openalex +1 more source
Peran IL-10 Dan Indeks Resistensi Arteri Uterina Dalam Memprediksi Pertumbuhan Janin Terhambat Pada Preeklamsia Onset Dini [PDF]
, 2015 Tujuan: Melihat hubungan IL-10 dantahanan arteri uterina terhadap kejadian PJT intrauterin pada pasien preeklampsia berat.Bahan dan Metode: Penelitian kami adalah analitik cross sectional yang dilakukan pada 40 wanita hamil usia 30-34 minggu yang ...
Ernawati, E. (Ernawati) +1 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Transfer of genes for IL-10 and TGF-β to isolated human pancreatic islets
, 1997 Shaoping Deng +7 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source