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IL-10 in Systemic Lupus Erythematosus: Balancing Immunoregulation and Autoimmunity. [PDF]

open access: yesInt J Mol Sci
Richter P   +5 more
europepmc   +1 more source

Functional differences between CLL- and ALL-derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL-10 as potential modulatory targets. [PDF]

open access: yesHemasphere
Dingfelder J   +15 more
europepmc   +1 more source
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IL‐10 and IL‐10 receptor defects in humans

Annals of the New York Academy of Sciences, 2011
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is chronic in nature and is characterized by abdominal pain, diarrhea, bleeding, and malabsorption. It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria
Erik-Oliver, Glocker   +4 more
openaire   +2 more sources

IL-10 in Humans: Lessons from the Gut, IL-10/IL-10 Receptor Deficiencies, and IL-10 Polymorphisms

2014
Inflammatory bowel disease (IBD) represents a heterogeneous group of gastrointestinal disorders, where commensal gut flora provokes an either (a) insufficient or (b) uncontrolled immune response. This results either in a lack of or in excessive inflammation mainly manifesting as Crohn's disease or ulcerative colitis.
Engelhardt, Karin R., Grimbacher, Bodo
openaire   +3 more sources

Title: IL-10-producing T cells and their dual functions.

Seminars in Immunology, 2019
Interleukin (IL)-10 is considered a prototypical anti-inflammatory cytokine, which significantly contributes to the maintenance and reestablishment of immune homeostasis. However, this classical view fails to fully describe the pleiotropic roles of IL-10.
T. Bedke   +4 more
semanticscholar   +1 more source

IL-10 in Myeloma Cells

Leukemia & Lymphoma, 2002
In addition to interleukin (IL)-6, IL-10 is considered as one of the most important cytokines regulating the proliferation and cellular characteristics of myeloma cells. It is still unclear from the clinical data how serum IL-10 levels of various stages of myeloma, are related to clinical manifestations of this disease.
Takemi, Otsuki   +7 more
openaire   +2 more sources

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