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Functional Characterization of Human IL-10

International Archives of Allergy and Immunology, 1992
Rapid progress has been made over the past two years in the characterization of the biological activities of interleukin-10. Interleukin-10, produced by T cells, B cells, macrophages/monocytes and keratinocytes, alters profoundly the morphology, the expression of MHC class II antigens and the production of cytokines by monocytes which in turn can ...
H, Spits, R, de Waal Malefyt
openaire   +2 more sources

Alternative Activation of Macrophage by IL-10

Pathobiology, 1999
Macrophage activation by proinflammatory stimuli is suppressed by IL-10. We tested the hypothesis that IL-10 induces an alternative state of macrophage activation rather than solely mediating suppression. We therefore searched for genes the expression of which might be up-rather than downregulated in response to IL-10. Total RNA was obtained from mouse
R, Stumpo, M, Kauer, S, Martin, H, Kolb
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Interleukin-10 (IL-10)

1995
In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
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Progress of IL-10 and liver metastasis

Cytokine
Liver metastasis can occur in a wide range of cancers and have a significant impact on patient survival and prognosis. Once liver metastasis occurs, patients often lose the opportunity for surgery, and although a small percentage of patients can undergo hepatic resection to prolong survival, the benefit is not great.
Chuanfei, Zeng   +6 more
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2018
The effect of Thiotriazoline ointment with silver nanoparticles on the level of IL-10 in serum and focus of damage at experimental thermal burns in rats was study. It was found that Thiotriazoline ointment with silver nanoparticles increases / normalizes the content of antiinflammatory cytokine IL-10 in focus and blood which deficiency occurs as a ...
openaire   +1 more source

Involvement of IL-10 gene polymorphism (rs1800896) and IL-10 level in the development of periimplantitis

Minerva Dental and Oral Science
Dental implant loss is the worst problem. Today, implant failure is precisely characterized, however the underlying reasons vary by instance. Multiple implant failures indicate genetic risk factors.This cross-sectional study included 80 subjects (15 peri-implantitis patients, 35 successful implants and 30 healthy controls); their mean age was 44.22±10 ...
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IL-10

2001
Katherine A. Fitzgerald   +3 more
openaire   +1 more source

Relative IL-10 deficiency and effects of IL-10 therapy in psoriasis

Journal of Dermatological Science, 1998
K. Asadullah   +7 more
openaire   +1 more source

Role of IL-10 and the IL-10 Receptor in Immune Responses

2014
A. Howes, L. Gabryšová, A. O'Garra
openaire   +1 more source

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