Results 271 to 280 of about 11,738,321 (294)
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The Emerging Role of IL‐10 in Pregnancy
American Journal of Reproductive Immunology, 1996International ...
Chaouat, G. +8 more
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The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor
The Journal of Immunology, 1997Abstract BCRF1 is an EBV homologue of human IL-10 (hIL-10) and is known as viral IL-10 (vIL-10). As found earlier for the effects of vIL-10 on mouse mast cells and CD4+ T cells, the efficiency of inhibition by vIL-10 of IL-2 production by human CD4+ T cell clones is approximately 1000-fold diminished compared with hIL-10.
Y, Liu +7 more
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IL-10 immunosuppression in transplantation
Current Opinion in Immunology, 1995The description of IL-10 as an immunosuppressive cytokine that inhibits numerous T-cell and antigen-presenting cell functions has led to the investigation of the role of IL-10 in graft acceptance and rejection, in both manipulated and unmanipulated experimental systems.
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Cytokine & Growth Factor Reviews, 2010
In 2001, six immune mediators (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26) were grouped into the so-called IL-10 family of cytokines based on their similarities with respect to the structure and location of their encoding genes, their primary and secondary protein structures, and the receptor complexes used.
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In 2001, six immune mediators (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26) were grouped into the so-called IL-10 family of cytokines based on their similarities with respect to the structure and location of their encoding genes, their primary and secondary protein structures, and the receptor complexes used.
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A Deficiency of Placental IL-10 in Preeclampsia
The Journal of Immunology, 1999Abstract Accommodation of the fetoplacental unit in human pregnancy requires maternal immune tolerance to this “semiallograft”. Local antiplacental immunity is modified by synthesis of uncommon histocompatibility Ags (e.g., HLA-G), growth factors, and cytokines by the placenta.
A, Hennessy +3 more
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2007
Soon after the principles of nonself immunological recognition were discovered, it was realized that the state of pregnancy seemingly presents a paradox. In an outbreed population, half of the fetal genes are paternal, thus the fetus may be considered a semi-allograft.
Shaun P. Murphy, Surendra Sharma
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Soon after the principles of nonself immunological recognition were discovered, it was realized that the state of pregnancy seemingly presents a paradox. In an outbreed population, half of the fetal genes are paternal, thus the fetus may be considered a semi-allograft.
Shaun P. Murphy, Surendra Sharma
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Development of an ELISA for bovine IL-10
Veterinary Immunology and Immunopathology, 2002The objective of the study was to develop an assay for bovine IL-10 that could be applied to analyses of immune responses and advance understanding of a variety of diseases of cattle. Recombinant bovine IL-10 (rbo IL-10) was transiently expressed in Cos-7 cells and shown to inhibit the synthesis of IFN gamma by bovine cells stimulated with antigen in ...
L S, Kwong +6 more
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Functional Characterization of Human IL-10
International Archives of Allergy and Immunology, 2009Rapid progress has been made over the past two years in the characterization of the biological activites of interleukin-10. Interleukin-10, produced by T cells, B cells, macrophages/monocytes and keratinocytes, alters profoundly the morphology, the expression of MHC class II antigens and the production of cytokines by monocytes which in turn can affect
H, Spits, R, de Waal Malefyt
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Alternative Activation of Macrophage by IL-10
Pathobiology, 1999Macrophage activation by proinflammatory stimuli is suppressed by IL-10. We tested the hypothesis that IL-10 induces an alternative state of macrophage activation rather than solely mediating suppression. We therefore searched for genes the expression of which might be up-rather than downregulated in response to IL-10. Total RNA was obtained from mouse
R, Stumpo, M, Kauer, S, Martin, H, Kolb
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1995
In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
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In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
openaire +2 more sources