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Oleic acid alleviates the pathogenesis of lupus by suppressing the activation of TLR signaling pathways through the STAT3/IL-10 axis. [PDF]
Hu Y +10 more
europepmc +1 more source
Author Correction: Foxp3 + Treg-derived IL-10 promotes colorectal cancer-derived lung metastasis. [PDF]
Shiri AM +14 more
europepmc +1 more source
Peste des petits ruminants virus (PPRV) modulates caprine dendritic cell function and induces immunosuppression through IL-10 upregulation. [PDF]
Nogales-Altozano P +3 more
europepmc +1 more source
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British Journal of Cancer, 2021
The prognosis for patients with glioblastoma (GBM), the most common and malignant type of primary brain tumour, is very poor, despite current standard treatments such as surgery, radiotherapy and chemotherapy. Moreover, the immunosuppressive tumour microenvironment hinders the development of effective immunotherapies for GBM.
Samuel S. Widodo +4 more
openaire +3 more sources
The prognosis for patients with glioblastoma (GBM), the most common and malignant type of primary brain tumour, is very poor, despite current standard treatments such as surgery, radiotherapy and chemotherapy. Moreover, the immunosuppressive tumour microenvironment hinders the development of effective immunotherapies for GBM.
Samuel S. Widodo +4 more
openaire +3 more sources
IL-10 or not IL-10: that is the question
Nature Immunology, 2007Four new papers focused on how interleukin 10–producing cells are induced have led to some unexpected and intriguing observations on the nature of interleukin 17–producing T helper cells.
Dragana Jankovic, Giorgio Trinchieri
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IL‐10 and IL‐10 receptor defects in humans
Annals of the New York Academy of Sciences, 2011Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is chronic in nature and is characterized by abdominal pain, diarrhea, bleeding, and malabsorption. It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria
Erik-Oliver, Glocker +4 more
openaire +2 more sources
IL-10 in Humans: Lessons from the Gut, IL-10/IL-10 Receptor Deficiencies, and IL-10 Polymorphisms
2014Inflammatory bowel disease (IBD) represents a heterogeneous group of gastrointestinal disorders, where commensal gut flora provokes an either (a) insufficient or (b) uncontrolled immune response. This results either in a lack of or in excessive inflammation mainly manifesting as Crohn's disease or ulcerative colitis.
Engelhardt, Karin R., Grimbacher, Bodo
openaire +3 more sources

