Results 151 to 160 of about 1,832,666 (293)

IL-2 antibodies in type 1 diabetes and during IL-2 therapy [PDF]

Diabetologia, 2018
Churlaud, Guillaume, Rosenzwajg, Michelle, Cacoub, Patrice, Saadoun, David, Valteau-Couanet, Dominique, Chaput, Nathalie, Pugliese, Alberto, Klatzmann, David   +7 more
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The role of IL-2 in type 2 immunity. [PDF]

Front Immunol
Tatsumi N, Kumamoto Y.
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Induction of high numbers of T_reg cells post treatment with anti-IL-2/IL-2 complex associates with alleviation of experimental psoriasis-like skin inflammation. [PDF]

BMC Immunol
Salman S, Khalil SM, Abdel-Latif AM, El Attar YA, Salem ML.   +4 more
europepmc   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Elderly female CTLs maintain their initial activation and cytotoxicity independent of IL-2. [PDF]

Immun Ageing
Hof C, Angenendt A, Janku S, Jarzembowski L, Seelert K, Zöphel D, Hoth M, Lis A.   +7 more
europepmc   +1 more source

IL-2 and IL-4 Double Knockout Mice Reject Islet Allografts: A Role for Novel T Cell Growth Factors in Allograft Rejection [PDF]

, 1998
Li X, Prabir Roy‐Chaudhury, Wayne W. Hancock, Roberto Ceratti Manfro, Martin S. Zand, Yongsheng Li, Xin Xiao Zheng, Peter Nickerson, Jürg Steiger, Thomas R. Malek, Terry B. Strom   +10 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Low Dose of IL-2 Application for Graft-Versus-Host Disease Prophylaxis Following Haploidentical Stem Cell Transplantation. [PDF]

MedComm (2020)
Xu ZL, Lv M, Yu XX, Ding YY, Han TT, Fu HX, Zhang YY, Mo XD, Sun YQ, Xu LP, Zhang XH, Wang Y, Huang XJ, Zhao XY.   +13 more
europepmc   +1 more source