Results 191 to 200 of about 1,832,666 (293)

IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation [PDF]

, 2013
Seon-Yeong Lee, Seung‐Ki Kwok, Hye‐Jin Son, Jun‐Geol Ryu, Eun‐Kyung Kim, Hye‐Jwa Oh, Mi‐La Cho, Ji Hyeon Ju, Sung‐Hwan Park, Ho‐Youn Kim   +9 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Non-α-biased IL-2 enhances both intratumoral and subcutaneous CpG/α-OX40 therapy, unleashing systemic antitumor immunity in mice. [PDF]

J Immunother Cancer
Huang K, Ding X, Wen X, Huang C, Chen Y, Zhou X, Zhou L, He Y, Bai Z, Zhang C, Jin Y, Li J, Fei Z, Li W, Chen C.   +14 more
europepmc   +1 more source

IL-2 receptor; IL-2 receptor β-chain (IL2RB; CD122) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models [PDF]

Zilong Wang, Zhicheng Liu, Jiarui Zheng, Lin-Xiang Huang, Rui Jin, Xiaoxiao Wang, Dongbo Chen, Yandi Xie, Bo Feng   +8 more
openalex   +1 more source

The Dual Role of IL-2 in the Generation and Maintenance of CD8+ Memory T Cells [PDF]

, 2000
Zhenhua Dai, Bogumila T. Konieczny, Fadi G. Lakkis   +2 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines. [PDF]

Proc Natl Acad Sci U S A
Sobral MC, Cabizzosu L, Kang SJ, Ruark K, Najibi AJ, Lane RS, Vitner E, Ijaz H, Dellacherie MO, Dacus MT, Tringides CM, Lázaro I, Pittet MJ, Müller S, Turley SJ, Mooney DJ.   +15 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythematosus. [PDF]

Front Med (Lausanne)
Xia X, Qu R.
europepmc   +1 more source