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Dual Inhibition of IL-12/IL-23 and Selective Inhibition of IL-23 in Psoriasis
2018The etiology of psoriasis is unknown, although it is generally believed to be a complex T cell-mediated inflammatory disease with a genetic basis [1, 2]. CD4+ T helper cells, called T helper (Th) 17 cells, are important in the pathogenesis of psoriasis [2–5].
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IL-23 induced signaling and IL-23 receptor expression in human CD4 T cells
Cytokine, 2009Nor Fazila Che Mat +2 more
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