Results 91 to 100 of about 2,340,150 (306)
The impact of high density receptor clusters on VEGF signaling [PDF]
EPTCS 125, 2013, pp. 37-52, 2013 Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates receptor dimerization.
arxiv +1 more source
Expression of interleukin 2 receptors on activated human B cells. [PDF]
, 1984 Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF +8 more
core
Pleiotropic Effects of IL-2 on Cancer: Its Role in Cervical Cancer
Mediators of Inflammation, 2016 IL-2 receptor (IL-2R) signalling is critical for normal lymphocyte proliferation, but its role in cervical cancer is not fully understood. The receptor is composed of three chains: IL-2α, IL-2β, and IL-2γ.
Arturo Valle-Mendiola +4 more
doaj +1 more source
Cargo binding promotes KDEL receptor clustering at the mammalian cell surface [PDF]
Sci. Rep. 6, 28940, 2016, 2017 Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from chemotactic receptors in bacteria to ...
arxiv +1 more source
The Tohoku Journal of Experimental Medicine, 1992 We previously demonstrated the existence of a third component, p64, of IL-2 receptor (IL-2R), tentatively named the gamma chain of IL-2R. Our recent studies provided evidence suggesting that the gamma chain endows the beta chain of IL-2R with IL-2 binding ability.
K. Ohbo +6 more
openaire +4 more sources
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells [PDF]
, 2013 BackgroundActivation of the group 2 innate lymphoid cell (ILC2) population leads to production of the classical type 2 cytokines, thus promoting type 2 immunity.
Xue, Luzheng +7 more
core +2 more sources
F1000Research, 2017 Interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21 form a family of cytokines based on the sharing of a receptor component, the common cytokine receptor γ chain, γc, which is encoded by the gene mutated in humans with X-linked severe combined ...
Rosanne Spolski +2 more
doaj +1 more source
Critical role for prokineticin 2 in CNS autoimmunity [PDF]
, 2015 Objective: To investigate the potential role of prokineticin 2 (PK2), a bioactive peptide involved in multiple biological functions including immune modulation, in CNS autoimmune demyelinating disease.
ABOU HAMDAN M +16 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1994 Late-phase human T-cell lymphotropic virus I-associated adult T-cell leukemia cells express IL-2 receptors (IL-2R) but no longer produce IL-2.
R. Bamford +8 more
semanticscholar +1 more source
An Empirical Study of Immune System Based On Bipartite Network [PDF]
arXiv, 2007 Immune system is the most important defense system to resist human pathogens. In this paper we present an immune model with bipartite graphs theory. We collect data through COPE database and construct an immune cell- mediators network. The act degree distribution of this network is proved to be power-law, with index of 1.8.
arxiv