Structure-function relationships for the IL 2-receptor system. II. Localization of an IL 2 binding site on high and low affinity receptors. [PDF]
Li-Mei Kuo, C M Rusk, R J Robb
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The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses. [PDF]
T helper 17 cells (Th17) are critical for fighting infections at mucosal surfaces; however, they have also been found to contribute to the pathogenesis of multiple autoimmune diseases and have been targeted therapeutically.
Anderson, Mark S+6 more
core
Comparison of the expression of IL 2 receptors by human T and B cells: induction by the polyclonal mitogens, phorbol myristate acetate, and anti-mu antibody. [PDF]
Takeshi Suzuki, Max D. Cooper
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IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. [PDF]
Emerging evidence suggests that the T helper 17 (T(H)17) subset of αβ T cells contributes to the development of allergic asthma. In this study, we found that mice lacking the αvβ8 integrin on dendritic cells did not generate T(H)17 cells in the lung and ...
Atabai, Kamran+11 more
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Developmentally controlled expression of IL 2 receptors and of sensitivity to IL 2 in a subset of embryonic thymocytes. [PDF]
Cornelia Hardt+2 more
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Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage. [PDF]
Recent evidence suggests that T cells expressing gamma/delta antigen receptors (T cell receptor [TCR]) are subject to positive selection during development.
Allison, JP+5 more
core
Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity. [PDF]
He L+6 more
europepmc +1 more source
Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level. [PDF]
John C. Reed+3 more
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The beta-chain of the IL-2 receptor (p70) is tyrosine-phosphorylated on YT and HUT-102B2 cells. [PDF]
M Sharon+2 more
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