Results 271 to 280 of about 2,340,150 (306)
Some of the next articles are maybe not open access.
Science, 1987
Interleukin-2 (IL-2) induces cytolytic activity and proliferation of human blood lymphocytes. Yet, prior to activation, these cells do not express IL-2 receptors recognized by monoclonal antibodies to the Tac antigen.
Jay P. Siegel +3 more
semanticscholar +1 more source
Interleukin-2 (IL-2) induces cytolytic activity and proliferation of human blood lymphocytes. Yet, prior to activation, these cells do not express IL-2 receptors recognized by monoclonal antibodies to the Tac antigen.
Jay P. Siegel +3 more
semanticscholar +1 more source
European Journal of Immunology, 1995
AbstractMouse fibroblasts do not ordinarily express components for the interleukin‐2 receptor (IL‐2Rα, β, and γ). An analysis of these cells by reverse transcription followed by polymerase chain reaction, however, indicates the presence of transcripts specific for the IL‐2R β and γ genes. Transfection of the cDNA for the α chain of the human IL‐2R into
Bruno Azzarone +8 more
openaire +3 more sources
AbstractMouse fibroblasts do not ordinarily express components for the interleukin‐2 receptor (IL‐2Rα, β, and γ). An analysis of these cells by reverse transcription followed by polymerase chain reaction, however, indicates the presence of transcripts specific for the IL‐2R β and γ genes. Transfection of the cDNA for the α chain of the human IL‐2R into
Bruno Azzarone +8 more
openaire +3 more sources
Transcription and translation dependent induction of interleukin 2 (IL-2) and IL-2 receptors
Immunology Letters, 1984Our previous findings on the expression of Interleukin 2 (IL-2) receptors have shown that under the influence of certain drugs, it was possible to dissociate IL-2 production from the appearance of IL-2 receptors on human peripheral blood lymphocytes (PBL).
A.L. de Weck +3 more
openaire +3 more sources
Differential Effects of IL-2 and IL-15 on Expression of IL-2 Receptor α
Biochemical and Biophysical Research Communications, 2001IL-2 and IL-15 have overlapping functions since they share the IL-2Rbetagamma receptor complex. However, each cytokine has a private alpha receptor namely IL-2Ralpha for IL-2 and IL-15Ralpha for IL-15. As a consequence the effects of the two cytokines may differ.
Adelkrim Alileche +2 more
openaire +3 more sources
Hybridoma, 1985
Murine splenocytes immune to influenza virus-activated human T-cells were fused with SP2/0 cells, selected in chemically defined HAT media, and subcloned to yield a monoclonal antibody (MAb) termed 7G7/B6.
L. Rubin +4 more
semanticscholar +1 more source
Murine splenocytes immune to influenza virus-activated human T-cells were fused with SP2/0 cells, selected in chemically defined HAT media, and subcloned to yield a monoclonal antibody (MAb) termed 7G7/B6.
L. Rubin +4 more
semanticscholar +1 more source
IL 2 receptor induction on human T lymphocytes: role for IL 2 and monocytes.
The Journal of Immunology, 1985Abstract In this report we studied the requirements for the activation and proliferation of highly purified human T lymphocytes. Purified T cells incubated for 3 days with PHA neither proliferate nor express IL 2 receptors as detected by FACS analysis with the use of anti-Tac antibodies.
H, Wakasugi +3 more
openaire +2 more sources
The Journal of Immunology, 1985
Abstract The accessory cell requirements for the induction of the IL 2 receptor by the lectin Con A on murine T cell subsets were directly assayed with anti-IL 2 receptor monoclonal antibodies. Substantial levels of IL 2 receptor expression were induced on T lymphocytes of the MHC class I-restricted, suppressor/cytotoxic phenotype (L3T4-,
T R, Malek, J A, Schmidt, E M, Shevach
openaire +2 more sources
Abstract The accessory cell requirements for the induction of the IL 2 receptor by the lectin Con A on murine T cell subsets were directly assayed with anti-IL 2 receptor monoclonal antibodies. Substantial levels of IL 2 receptor expression were induced on T lymphocytes of the MHC class I-restricted, suppressor/cytotoxic phenotype (L3T4-,
T R, Malek, J A, Schmidt, E M, Shevach
openaire +2 more sources
IL-2-PE40 is cytotoxic for activated T lymphocytes expressing IL-2 receptors.
The Journal of Immunology, 1988Abstract IL-2-PE40 is a chimeric molecule in which IL-2 is attached to the amino end of modified Pseudomonas exotoxin molecule lacking cell recognition domain. This molecule was extremely toxic for Con A-stimulated spleen cells from mice. Moreover, IL-2-PE40 has suppressive effect against Ag-activated cells; it inhibits the generation of
M, Ogata +3 more
openaire +2 more sources
Soluble IL‐2 receptors in acute and subacute encephalitis
Annals of Neurology, 1987AbstractElevated levels of soluble interleukin‐2 receptors were present in the serum from patients with acute primary and postinfectious encephalitis and subacute sclerosing panencephalitis. In addition, soluble interleukin‐2 receptors were detected in the cerebrospinal fluid from patients with acute primary encephalitis.
D L Nelson +5 more
openaire +2 more sources
Structural Studies of T200 Glycoprotein and the Il-2 Receptor
Journal of Receptor Research, 1987Immunological analysis of the cell surface of hematopoietic cells has led to the identification of many different cell membrane molecules, some of which have well-defined functions as receptors. In general, however, the role of most lymphocyte cell surface molecules remains ill-defined even in cases in which antibody inhibition studies have given some ...
S. Ralph +3 more
openaire +3 more sources