Results 301 to 310 of about 1,399,966 (352)

Oxytocin Modulates Microglial IL-17-Linked Inflammatory Pathways Through the IL-6/COX-2. [PDF]

Life (Basel)
Hwang W, Jang YH, Hong J, Kang S, Hur JK, Lee HJ.   +5 more
europepmc   +1 more source

Low IgE and absence of sensitization in non-T2 asthma: a transcriptomic and cytokine study. [PDF]

Front Immunol
Lee JH, Lin YT, Wang LC, Yu HH, Hu YC, Yang YH, Chiang BL.   +6 more
europepmc   +1 more source

IL-33 Drives Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension. [PDF]

Hypertension
Jankauskas SS, Kansakar U, Varzideh F, Santulli G.   +3 more
europepmc   +1 more source

Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]

Mediators Inflamm
Farahani H, Kokhaei P, Ganji A, Mosayebi G, Ghazavi A.   +4 more
europepmc   +1 more source

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The IL-2/IL-2 receptor system: A current overview

Cell, 1993
Tadatsugu Taniguchi and Yasuhiro Mlnami Institute for Molecular and Cellular Biology Osaka University Yamadaoka 1-3, Suita-shi Osaka 565 Japan The discovery and molecular characterization of interleu- kin-2 (IL-2) has had a considerable impact on basic and clinical immunology(Morgan et al., 1976; Taniguchi et al., 1963; Rosenberg et al., 1965).
T, Taniguchi, Y, Minami
openaire   +2 more sources

17-β-ESTRADIOL SUPPRESSES IL-2 AND IL-2 RECEPTOR

Cytokine, 2001
Interleukin-2 (IL-2) plays an important role in adaptive immune responses. These responses differ between females and males and may be due to the sex steroid estrogen. In this investigation we show that estrogen suppresses IL-2 production from activated peripheral blood T cells and CD4+ T cell lines at the transcriptional level.
R W, McMurray, K, Ndebele, K J, Hardy, J K, Jenkins   +3 more
openaire   +2 more sources

Immunotherapy through the IL-2 receptor

Immunologic Research, 1992
The IL-2 receptor system is a suitable target for immunotherapy in conditions in which activated (T) cells play a pivotal role, such as transplantation reactions and auto-immune diseases. Antibodies directed at the IL-2R can be used as such or modified by conjugation to toxins or through chelators to radiolabels.
H A, Verheul, M, Verveld, E S, Bos
openaire   +2 more sources

DIFFERENTIAL IL-2 RECEPTOR EXPRESSION IN RENAL ALLOGRAFT RECIPIENTS TREATED WITH AN ANTI-IL-2-RECEPTOR ANTIBODY

Transplantation, 1989
Patients were entered into a randomized trial of prophylaxis for renal allograft rejection by the administration of an anti-human IL-2 receptor antibody, anti-Tac, during the first ten days posttransplant. Interleukin-2 receptor (IL-2 R) expression was measured using two anti-IL-2 R monoclonal antibodies (moAbs), anti-Tac and 1HT4-4H3.
E L, Ramos, E L, Milford, R L, Kirkman, N L, Tilney, T B, Strom, M E, Shapiro, T A, Waldmann, I G, Wood, M R, Rollins, C B, Carpenter   +9 more
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Protein phosphorylation mediated by IL-2/IL-2 receptor beta-chain interaction.

The Journal of Immunology, 1988
Abstract We previously found that IL-2 rapidly induced protein phosphorylation of a 67-kDa (pp67) and four 63-kDa (pp63s) cellular proteins in various T cells. Here, we show that the IL-2-stimulated phosphorylation is mediated by the IL-2R beta-chain composed of the high affinity IL-2R, and induced by activation of Ca2+/phospholipid ...
T, Ishii, T, Takeshita, N, Numata, K, Sugamura   +3 more
openaire   +2 more sources

Highlight: IL-2 receptor signaling

Science Signaling, 2017
Two papers reveal the consequences of altered interleukin-2 receptor signaling in T lymphocytes.
openaire   +1 more source