Results 111 to 120 of about 961,718 (249)

The Effect of Interleukin 38 on Angiogenesis in a Model of Oxygen-induced Retinopathy

Scientific Reports, 2017
Interleukin 38 (IL-38) is a novel identified cytokine of IL-1 family in which some members are important in inflammation and angiogenesis. However, the role of IL-38 in regulating angiogenesis is unknown.
Jing Zhang, Ruijuan Zhao, Jianping Chen, Jiayi Jin, Ying Yu, Yunzhe Tian, Weihua Li, Wencong Wang, Hongyan Zhou, Shao Bo Su   +9 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Bostonia: The Boston University Alumni Magazine. Volume 37 [PDF]

, 1963
Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and ...
Christian, Frank, Gould, Samuel, Kennedy, Edward, Montagu, Ashley   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interleukin-38 overexpression in keratinocytes limits desquamation but does not affect the global severity of imiquimod-induced skin inflammation in mice

Frontiers in Immunology
Psoriasis is a common chronic inflammatory skin disease that significantly impacts the patients’ quality of life. Recent studies highlighted the function of the interleukin (IL)-1 family member IL-38 in skin homeostasis and suggested an anti-inflammatory
Arnaud Huard, Arnaud Huard, Arnaud Huard, Emiliana Rodriguez, Emiliana Rodriguez, Emiliana Rodriguez, Dominique Talabot-Ayer, Dominique Talabot-Ayer, Dominique Talabot-Ayer, Andreas Weigert, Gaby Palmer, Gaby Palmer, Gaby Palmer   +12 more
doaj   +1 more source

Diventare ingegnere un gioco da ragazze [PDF]

, 2015
La mancanza di ragazze nelle facoltà tecnico-scientifiche ha un costo economico e sociale molto alto, questo è ormai un dato di fatto di cui sono consapevoli anche i governi.
Baumgartner, Emma, Catarci, Tiziana, D'Orazio, Annunziata, Daraio, Cinzia, Lamedica, Regina, Salinetti, Gabriella, Simonazzi, Annamaria   +6 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Bioagricoltura per gli insetti utili [PDF]

, 2017
La bioagricoltura favorisce gli insetti utili e riduce il carico di pesticidi.
Pfiffner, Lukas
core  

Assessment of IL-38 And IL-40 Levels in Gingival Crevicular Fluid in Gingivitis and Stage III Grade C Periodontitis: A Comparative Clinical Study [PDF]

Periodontal diseases are infections of the supporting apparatus of teeth caused by microbial agents, and cytokines have an important role in the inflammatory response.
Das, Dr. Neelam
core   +2 more sources