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Circulating interleukin-38 concentrations in healthy adults [PDF]
Interleukin (IL)-38 is the latest discovered member of the interleukin-1 family, which has anti-inflammatory properties similar to IL-36Ra. Several studies compared circulating IL-38 concentrations in healthy and diseased populations to characterize its ...
Lisa U. Teufel +10 more
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Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients [PDF]
Introduction A major contributor to coronavirus disease 2019 (COVID‐19) progression and severity is a dysregulated innate and adaptive immune response. Interleukin‐38 (IL−38) is an IL‐1 family member with broad anti‐inflammatory properties, but thus far ...
Dennis M. deGraaf +12 more
doaj +2 more sources
Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression [PDF]
Lung cancer continues to be the leading cause of cancer-related deaths worldwide due to its high incidence, malignant behaviour and lack of major advancements in treatment strategy.
Feng Wang +3 more
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Interleukin-38 and cardiovascular pathology: literature review [PDF]
Cardiovascular pathology is a leading cause of morbidity and mortality. An important task of modern cardiology is the search and study of new biological markers. Scientists’ interest is actively focused on the study of interleukin-38.
Amina M. Alieva +4 more
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Objective To investigate the roles of cytokines, IL-36γ and IL-38, in the inflammatory response in psoriasis vulgaris. Methods Both serum and peripheral blood mononuclear cells (PBMC) were collected from 29 patients with psoriasis vulgaris (PV) and 19 ...
Jiao ZHANG +4 more
doaj +1 more source
Anti-inflammatory Mechanisms of IL-38 in Chinese Patients with Allergic Rhinitis [PDF]
Background: T-helper 17 (Th17) cell response is engaged in the onset of allergic rhinitis (AR). Moreover, interleukin (IL)-38 is thought to be involved in inhibiting cytokine secretion in the Th17 pathway.Objective: To evaluate the regulatory function of
Xiaoqiang Wang +3 more
doaj +1 more source
Background In psoriasis, interleukin (IL)-36 is considered a pathogenic driver, whereas IL-38 was downregulated. Little is known about their role in metabolic syndrome (Ms) in psoriasis.
Marwa A Amer +6 more
doaj +1 more source
Effects of IL-38 on Macrophages and Myocardial Ischemic Injury
Macrophages play an important role in clearing necrotic myocardial tissues, myocardial ischemia–reperfusion injury, and ventricular remodeling after myocardial infarction.
Zhiyang Li +10 more
doaj +1 more source
Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma
Background Bronchial asthma is considered the most prevalent chronic respiratory disease worldwide and is one of the main causes of hospitalization in the pediatric population.
Asmaa Kamal +3 more
doaj +1 more source
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang +6 more
doaj +1 more source

