Results 31 to 40 of about 2,027,182 (132)

Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections [PDF]

open access: yesCell Death and Disease, 2021
Interleukin-38 has recently been shown to have anti-inflammatory properties in lung inflammatory diseases. However, the effects of IL-38 in viral pneumonia remains unknown.
Xun Gao   +9 more
doaj   +2 more sources

Emerging Role of Interleukin-38 (IL-38) in the Development of Rheumatoid Arthritis

open access: yesRheumatology and Therapy
Rheumatoid arthritis (RA) is an incurable autoimmune disease. The role of interleukin-38 (IL-38), an anti-inflammatory cytokine, in RA is not fully understood, and its clinical relevance in RA remains unclear. This study aims to investigate the correlation of IL-38 with disease activity and the clinical manifestation of RA.In this cross-sectional study,
Shengxiang Liang   +7 more
openaire   +3 more sources

Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma [PDF]

open access: yesCellular & Molecular Immunology, 2019
Abstract We elucidated the anti-inflammatory mechanisms of IL-38 in allergic asthma. Human bronchial epithelial cells and eosinophils were cocultured upon stimulation with the viral RLR ligand poly (I:C)/LyoVec or infection-related cytokine TNF-α to induce expression of cytokines/chemokines/adhesion molecules.
Xiaoyu Sun   +9 more
openaire   +3 more sources

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +492 more
core   +8 more sources

Recombinant IL-38 Alleviates Temporomandibular Joint Synovial Inflammation via IL-1R1-NF-κB-IL1β Pathway [PDF]

open access: yesInternational Dental Journal
Introduction and aims: Interleukin (IL)-38 has been identified as an anti-inflammatory cytokine; however, its specific role in temporomandibular joint (TMJ) synovial inflammation and the identity of its functional receptors remain elusive.
Ping Luo   +3 more
doaj   +2 more sources

Association of interleukin-38 and its polymorphism (rs7599662) with ulcerative colitis

open access: yesThe Egyptian Journal of Internal Medicine
Abstract Background Ulcerative colitis (UC) is a common health issue worldwide. IL-38 is a cytokine that was verified to have anti-inflammatory role and associated with many inflammatory and immune disorders.
Soha M. Hamdy   +3 more
openaire   +2 more sources

Imbalance of expression levels of IL-36γ and IL-38 is possibly associated with the severity of inflammation in psoriasis vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To investigate the roles of cytokines, IL-36γ and IL-38, in the inflammatory response in psoriasis vulgaris. Methods Both serum and peripheral blood mononuclear cells (PBMC) were collected from 29 patients with psoriasis vulgaris (PV) and 19 ...
Jiao ZHANG   +4 more
doaj   +1 more source

Anti-inflammatory Mechanisms of IL-38 in Chinese Patients with Allergic Rhinitis [PDF]

open access: yesIranian Journal of Immunology, 2023
Background: T-helper 17 (Th17) cell response is engaged in the onset of allergic rhinitis (AR). Moreover, interleukin (IL)-38 is thought to be involved in inhibiting cytokine secretion in the Th17 pathway.Objective: To evaluate the regulatory function of
Xiaoqiang Wang   +3 more
doaj   +1 more source

Imbalance between serum interleukin-36 and interleukin-38 is associated with metabolic syndrome in psoriasis vulgaris

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2023
Background In psoriasis, interleukin (IL)-36 is considered a pathogenic driver, whereas IL-38 was downregulated. Little is known about their role in metabolic syndrome (Ms) in psoriasis.
Marwa A Amer   +6 more
doaj   +1 more source

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]

open access: yes, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core   +4 more sources

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