Results 31 to 40 of about 1,897,702 (279)
The decreased serum levels of interleukin-38 in patients with gout and its clinical significance [PDF]
Frontiers in ImmunologyBackgroundInterleukin (IL)-38 is a newly discovered anti-inflammatory cytokine. However, its concentration and clinical significance in patients with gout remain unclear.
Hua Huang +7 more
doaj +2 more sources
Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease. [PDF]
Cytokine, 2021 Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the anti-inflammatory properties of IL-38 in murine models of arthritis and systemic ...
de Graaf DM +12 more
europepmc +2 more sources
Elevated serum interleukin-38 levels in polymyositis and dermatomyositis: diagnostic implications and correlations with inflammatory markers [PDF]
Frontiers in ImmunologyBackgroundInterleukin (IL)-38 has been recently identified as an anti-inflammatory cytokine. Polymyositis (PM) and dermatomyositis (DM) are two prevalent clinical inflammatory myopathies.
Wen Qin +9 more
doaj +2 more sources
Interleukin-38 as a potential diagnostic biomarker for heart failure. [PDF]
Biomark MedInterleukin-38 (IL-38) attenuates inflammation, myocardial injury, and ventricular remodeling after myocardial infarction, which potentially reduces the incidence of heart failure (HF). This study aimed to evaluate the diagnostic value of IL-38 for HF.IL-38 was detected via enzyme-linked immunosorbent assay in the serum samples of 238 hF patients and ...
Liu H +7 more
europepmc +3 more sources
Interleukin-38 protects against sepsis by augmenting immunosuppressive activity of CD4+ CD25+ regulatory T cells. [PDF]
J Cell Mol Med, 2020 Naturally occurring CD4+CD25+ regulatory T cells (Tregs) are required to limit immune‐induced pathology and to maintain homeostasis during the early‐phase of sepsis.
Ge Y, Huang M, Wu Y, Dong N, Yao YM.
europepmc +2 more sources
Interleukin-38 in colorectal cancer: a potential role in precision medicine. [PDF]
Cancer Immunol Immunother, 2020 Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising sensitive/specific marker(s).
Chen F +5 more
europepmc +3 more sources
The Egyptian Journal of Internal MedicineBackground Interleukin (IL)-36α and IL-38, two novel cytokines of the IL-1 family, have recently been proposed to have a pathophysiological significance in type 2 diabetes mellitus (T2DM).
Shahad W. Nassurat +2 more
doaj +2 more sources
Interleukin-38: A Candidate Biomarker for Disease Severity in Advanced Steatotic Liver Disease [PDF]
CellsBackground: Interleukin-38 (IL-38) is an anti-inflammatory IL-1—family cytokine implicated in limiting tissue injury by its anti-inflammatory character. We evaluated the diagnostic discrimination and prognostic relevance in steatotic liver disease (SLD).
Valeria Wagner +8 more
doaj +2 more sources
Cellular Physiology and Biochemistry, 2018 Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang +6 more
doaj +2 more sources
Egyptian Journal of Medical Human GeneticsBackground Interleukin-38 (IL-38), an inflammatory cytokine discovered in recent years, has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). IL-38 is encoded by the IL1F10 (interleukin 1 family member 10) gene.
Rawan A. Nijeeb +2 more
doaj +2 more sources