Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia [PDF]
, 2022 Background: Nutraceutical combinations (NCs) against hypercholesterolemia are increasing in the marketplace. However, the availability of NCs without monacolin K is scarce even though the statin-intolerant population needs it.
Antonicelli, Roberto +11 more
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Journal of the Egyptian Women’s Dermatologic Society, 2023 Background In psoriasis, interleukin (IL)-36 is considered a pathogenic driver, whereas IL-38 was downregulated. Little is known about their role in metabolic syndrome (Ms) in psoriasis.
Marwa A Amer +6 more
doaj +1 more source
Tonsillar transcriptional profiles in atopic and non‐atopic subjects [PDF]
, 2023 Background: Emerging research suggests that local lymphatic tissue such as tonsils have important role in regulating the immune responses. However, allergen sensitization-induced alterations in transcriptome of tonsils are not known.
Ahmad, Freed +9 more
core +5 more sources
Activation of Mast Cells by Neuropeptides: The Role of Pro-Inflammatory and Anti-Inflammatory Cytokines [PDF]
, 2023 Mast cells (MCs) are tissue cells that are derived from bone marrow stem cells that contribute to allergic reactions, inflammatory diseases, innate and adaptive immunity, autoimmunity, and mental disorders.
Ronconi, Gianpaolo
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Effects of IL-38 on Macrophages and Myocardial Ischemic Injury
Frontiers in Immunology, 2022 Macrophages play an important role in clearing necrotic myocardial tissues, myocardial ischemia–reperfusion injury, and ventricular remodeling after myocardial infarction.
Zhiyang Li +10 more
doaj +1 more source
Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma
The Egyptian Journal of Bronchology, 2022 Background Bronchial asthma is considered the most prevalent chronic respiratory disease worldwide and is one of the main causes of hospitalization in the pediatric population.
Asmaa Kamal +3 more
doaj +1 more source
Can Unconventional Immunomodulatory Agents Help Alleviate COVID-19 Symptoms and Severity? [PDF]
, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS coronavirus 2, or SARS-CoV-2) is the cause of the respiratory infection known as COVID-19. From an immunopathological standpoint, coronaviruses such as SARS-CoV-2 induce increased levels of a variety ...
Agrawal +26 more
core +2 more sources
The burden of calcific aortic stenosis. what's behind [PDF]
, 2023 In Western countries, calcific aortic valve stenosis (CAS) is widely common, representing the third cause of death among cardiovascular diseases (CVD). The burden of CAS is high, with an increasing prevalence rate related to age.
Bruno, N +6 more
core +1 more source
Evaluation of serum interleukin-36, interleukin-37 and interleukin-38 levels in rosacea patients [PDF]
, 2021 Tıp Fakültesi, Deri ve Zührevi Hast. Ana Bilim DalıGiriş ve Amaç: Rozasea, patogenezi halihazırda net olarak aydınlatılamamış olan, ön planda yüz cildinde dışbükey bölgelerde eritem, telenjiektazi, papül, püstül ve fimatöz lezyonlarla karakterize olan ve
Ekinci, Alper
core
An atlas of the knee joint proteins and their role in osteoarthritis defined by literature mining [PDF]
, 2023 [Abstract] Osteoarthritis (OA) is the most prevalent rheumatic pathology. However, OA is not simply a process of wear and tear affecting articular cartilage but rather a disease of the entire joint.
Blanco García, Francico J +7 more
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