Results 11 to 20 of about 1,897,702 (279)

Prognostic value of interleukin-34 and interleukin-38 in patients with newly diagnosed atrial fibrillation [PDF]

Frontiers in Cardiovascular Medicine, 2023
BackgroundInterleukin (IL)-34 and IL-38 are associated with cardiovascular disease (CVD). However, their involvement in atrial fibrillation (AF) and AF-associated adverse events remains uncertain. Therefore, we aimed to investigate their association with
Jiaxue Ma, Na Wu, Na Wu, Zhiquan Yuan, Zhiquan Yuan, Yanxiu Chen, Chengying Li, Chengying Li, Weijia Xie, Weijia Xie, Zhihui Zhang, Yafei Li, Yafei Li, Li Zhong   +13 more
doaj   +3 more sources

Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors [PDF]

Cell Communication and Signaling
Background Interleukin (IL)-38 is an IL-1 family cytokine that was proposed to exert anti-inflammatory effects. However, its mechanisms of action are not well understood and the identity of the IL-38 receptor(s) remains debated.
Alejandro Diaz-Barreiro, Dominique Talabot-Ayer, Arnaud Huard, Gea Cereghetti, Jenna Tonacini, Mike Maillasson, Antonio Francés-Monerris, Erwan Mortier, Gaby Palmer   +8 more
doaj   +4 more sources

Interleukin-38 overexpression in keratinocytes limits desquamation but does not affect the global severity of imiquimod-induced skin inflammation in mice [PDF]

Frontiers in Immunology
Psoriasis is a common chronic inflammatory skin disease that significantly impacts the patients’ quality of life. Recent studies highlighted the function of the interleukin (IL)-1 family member IL-38 in skin homeostasis and suggested an anti-inflammatory
Arnaud Huard, Arnaud Huard, Arnaud Huard, Emiliana Rodriguez, Emiliana Rodriguez, Emiliana Rodriguez, Dominique Talabot-Ayer, Dominique Talabot-Ayer, Dominique Talabot-Ayer, Andreas Weigert, Gaby Palmer, Gaby Palmer, Gaby Palmer   +12 more
doaj   +5 more sources

Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections [PDF]

Cell Death and Disease, 2021
Interleukin-38 has recently been shown to have anti-inflammatory properties in lung inflammatory diseases. However, the effects of IL-38 in viral pneumonia remains unknown.
Xun Gao, Paul Kay Sheung Chan, Grace Chung Yan Lui, David Shu Cheong Hui, Ida Miu-Ting Chu, Xiaoyu Sun, Miranda Sin-Man Tsang, Ben Chung Lap Chan, Christopher Wai-Kei Lam, Chun-Kwok Wong   +9 more
doaj   +3 more sources

Interleukin-38 alleviates cardiac remodelling after myocardial infarction. [PDF]

J Cell Mol Med, 2020
Excessive immune‐mediated inflammatory reaction plays a deleterious role in ventricular remodelling after myocardial infarction (MI). Interleukin (IL)‐38 is a newly characterized cytokine of the IL‐1 family and has been reported to exert a protective ...
Wei Y, Lan Y, Zhong Y, Yu K, Xu W, Zhu R, Sun H, Ding Y, Wang Y, Zeng Q.   +9 more
europepmc   +5 more sources

Evaluation of interleukin-38 levels in serum of patients with coronavirus disease 2019. [PDF]

J Med Virol, 2022
Interleukin‐38 (IL‐38) has recently been considered as a cytokine with anti‐inflammatory properties in viral respiratory infections, particularly coronavirus disease 19 (COVID‐19), but the evidence has not been well elucidated.
Al-Bassam WW, Al-Karaawi IA, Sharquie IK, Ad'hiah AH.   +3 more
europepmc   +4 more sources

Low serum interleukin-38 levels in patients with Graves' disease and Hashimoto's thyroiditis. [PDF]

J Clin Lab Anal, 2022
Autoimmune thyroid disease (AITD) mainly includes Graves’ disease (GD) and Hashimoto's thyroiditis (HT), which is caused by individual genetics, autoimmune dysfunction, and a variety of external environmental factors. Interleukin (IL)‐38 is involved in a
Xu J, Huang G, Weng L, Gong L, Mao Y, Li Y, Li M.   +6 more
europepmc   +5 more sources

The anti-inflammatory and protective role of interleukin-38 in inflammatory bowel disease. [PDF]

J Clin Biochem Nutr, 2022
Interleukin (IL)-38 exerts an anti-inflammatory function by binding to several cytokine receptors, including the IL-36 receptor. In this study, we evaluated IL-38 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD) and ...
Ohno M, Imai T, Chatani M, Nishida A, Inatomi O, Kawahara M, Hoshino T, Andoh A.   +7 more
europepmc   +5 more sources

Emerging Role of Interleukin-38 (IL-38) in the Development of Rheumatoid Arthritis

Rheumatology and Therapy
Introduction Rheumatoid arthritis (RA) is an incurable autoimmune disease. The role of interleukin-38 (IL-38), an anti-inflammatory cytokine, in RA is not fully understood, and its clinical relevance in RA remains unclear.
Shengxiang Liang, Liting Chen, Ruilan Liang, Jiayi Ling, Minghui Hou, Song Gao, Minglin Ou, Min Yang   +7 more
doaj   +4 more sources

Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma. [PDF]

Cell Mol Immunol, 2020
We elucidated the anti-inflammatory mechanisms of IL-38 in allergic asthma. Human bronchial epithelial cells and eosinophils were cocultured upon stimulation with the viral RLR ligand poly (I:C)/LyoVec or infection-related cytokine TNF-α to induce ...
Sun X, Hou T, Cheung E, Iu TN, Tam VW, Chu IM, Tsang MS, Chan PK, Lam CW, Wong CK.   +9 more
europepmc   +5 more sources