Results 171 to 180 of about 35,795 (270)

Trends in Corticosteroid Use and Excess in Patients With Inflammatory Bowel Disease in the United States, Sweden, and Denmark

JCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT Background and Aims Studies show that corticosteroid use in inflammatory bowel disease (IBD) exceeds guideline recommendations. To better understand patterns of corticosteroid use and identify factors associated with excess exposure, we examined long‐term trends in corticosteroid prescribing practices in large IBD populations across 3 ...
Tim Raine, Gil Y. Melmed, J. Casey Chapman, Bobby Lo, Jonas Söderling, Laura E. Targownik, Nidhi Shukla, Si Xuan, Elena Marced Barrachina, Dolly Sharma, Johan Burisch, Ola Olén   +11 more
wiley   +1 more source

Aging of the adaptive immune system affects the gut microbiome and systemic levels of vitamin B6. [PDF]

Microbiome
Stahl S, Widmaier H, Sakk V, Nalapareddy K, Kissmann AK, Rosenau F, Mulaw MA, Haslam DB, Geiger H.   +8 more
europepmc   +1 more source

Treatment Outcomes of Hospitalized Patients With Inflammatory Bowel Disease at a Tertiary Care Center in Nepal: A Cross‐Sectional Study

JCC Plus, Volume 1, Issue 4, July 2026.
Overall, patients with IBD constituted 1.6% (n = 37) of all admissions to the gastroenterology ward for any indication. Most (2/3rd) hospitalized patients with IBD responded to conventional therapy; one third required advanced therapy or surgery. In‐hospital mortality was high at 5%, probably related to delayed diagnosis, limited access to advanced ...
Ajay Kumar Yadav, Bhupendra Kumar Basnet, Ramila Shrestha, Ajit Khanal, Milan Shrestha, Mukesh Sharma Poudel   +5 more
wiley   +1 more source

Unusual course of a Bricker ileal conduit: stenosis from kinking and delayed bowel obstruction. [PDF]

Int J Surg Case Rep
Zheng Z, Tang F, Aers M, Liu T, Peng J.
europepmc   +1 more source

Mesenteric Lymphatic Dysfunction as the Initiating Event in Crohn's Disease: Toward an Outside‐In Paradigm

JCC Plus, Volume 1, Issue 4, July 2026.
Mesenteric lymphatic dysfunction promotes immune cell accumulation and chronic inflammation, leading to creeping fat formation. Progressive activity drives transmural inflammation. ABSTRACT Crohn's disease (CD) has traditionally been explained by an “inside‐out” model, in which disruption of the intestinal mucosal barrier allows luminal bacteria to ...
Takayuki Ogino, Yuki Sekido, Tsunekazu Mizushima, Mitsunobu Takeda, Tsuyoshi Hata, Atsushi Hamabe, Norikatsu Miyoshi, Mamoru Uemura, Yuichiro Doki, Hidetoshi Eguchi   +9 more
wiley   +1 more source

Monosodium glutamate-mediated Ca²⁺-dependent intestinal epithelial ion transports in health and IBS-D in male mice. [PDF]

Physiol Rep
Wang Y, Chu F, Gong Y, Guo R, Dong H.
europepmc   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Successful Surgical Resection for Protein-Losing Enteropathy Caused by Ischemic Ileitis. [PDF]

Surg Case Rep
Ueda K, Harada K, Yamana I, Fujikawa T.
europepmc   +1 more source

Sustained Treatment Success With Ustekinumab in Symptomatic Stricturing Crohn's Disease: A Retrospective Single‐Arm Observational Cohort Study

MedComm, Volume 7, Issue 7, July 2026.
Data on ustekinumab (UST) for symptomatic stricturing Crohn's disease remain scarce in China. This cohort study screened 73 patients from June 2022 to April 2024, of whom 54 were eligible included, with 81.5% achieving 52‐week treatment success. Most attained sustained clinical remission alongside improved inflammation and strictures. Nonsmoking status
Jingwen Liu, Wen Hu, Shuyan Li, Shurong Hu, Deming Jiang, Yan Chen   +5 more
wiley   +1 more source

Ileal Bile Acid Transporter Inhibitors for Symptomatic Cholestasis due to Vanishing Bile Duct Syndrome in Adults. [PDF]

ACG Case Rep J
Vignone A, Montecalvo D, Ferrari P, Nardelli S, Di Cola S, D'Amati G, Ascione A, Ginanni Corradini S, Parisse S, Ferri F, Scavalli AS, Alvaro D, Cardinale V.   +12 more
europepmc   +1 more source