Results 171 to 180 of about 2,175,268 (253)

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

The development of residential gut microbiota in mice at different phases in early life. [PDF]

iScience
Meng Y, Yin Y, Ouyang C, Lu F, Li X, Ren Y, Hao R.   +6 more
europepmc   +1 more source

Intracellular mechanosensation in intestinal smooth muscle: Piezo1 complexes amplify signalling beyond the surface

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanosensation is not confined to the cell surface. In intestinal smooth muscle Piezo1 is predominantly intracellular (86%), where it forms a nanoscale (<40 nm) complex at the sarcoplasmic reticulum (SR)–plasma membrane junction. Within this sensor–amplifier–effector axis intra‐Piezo1 is the sensor that detects force at the SR,
Geoanna M. Bautista, Declan Manning, Emily C. Lieu, Stephanie I. Ugochukwu, Collin Matsumoto, Joshua P. Tulman, Miguel Martin‐Aragon Baudel, Nuria Daghbouche‐Rubio, Steven J. McElroy, Sal A. Baker, Manuel F. Navedo, L. Fernando Santana   +11 more
wiley   +1 more source

Laparoscopic total colectomy, ileal J-pouch, and ileorectal anastomosis in the treatment of slow transit constipation: a case report (with video). [PDF]

Int J Surg Case Rep
Ma ZN, Zhang XW, Zhao XF.
europepmc   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

The Journal of Physiology, EarlyView.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

A Novel Epigenetic Mechanism of Intestinal NHE3 Gene Regulation by Histone Acetylation. [PDF]

Int J Mol Sci
Kumar A, Jayawardena D, Priyamvada S, Patel M, Coffing H, Kulkarni N, Anwar M, Anbazhagan AN, Malhotra P, Gill RK, Alrefai WA, Dudeja PK, Saksena S.   +12 more
europepmc   +1 more source

Curcumin Attenuates <i>Escherichia coli</i>-Induced Enteritis and Macrophage Inflammation in Broilers. [PDF]

Animals (Basel)
Xu H, Tang Y, Zhang S, Wang G.
europepmc   +1 more source

Case Report of a Rapidly Progressive Indolent T‐Cell Lymphoma of the Gastrointestinal Tract

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Indolent T‐cell lymphoma of the gastrointestinal tract (iTCL‐GI) is a relatively newly recognized disease entity. iTCL‐GI was first proposed by Perry et al. in 2013, before it was formally incorporated as a distinct disease category in the fifth edition of the World Health Organization Classification of Hematolymphoid Tumors: Lymphoid ...
Keitaro Shibuya, Akiko Tamura, Daiki Yafuso, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Hiromichi Shimizu, Toshimitsu Fujii, Kazuo Ohtsuka, Ryuichi Okamoto   +9 more
wiley   +1 more source

β-Hydroxybutyrate precursor 1,3-butanediol modulates enteric pathogen susceptibility and Th17 responses via commensal bacteria. [PDF]

mSystems
Dong W, Yan C, Korwin-Mihavics B, Stack K, Hughes G, Schmidt A, Schwartz KJ, Caballero-Flores G, Alexander M.   +8 more
europepmc   +1 more source

Endoscopic Management of Pouch Volvulus as a Complication of Ileal Pouch Anal Anastomosis in Patients With Ulcerative Colitis. [PDF]

ACG Case Rep J
Kareddy V, Ioannou S, Deshpande AR.
europepmc   +1 more source