Results 161 to 170 of about 194,648 (336)
Grape Seed Proanthocyanidins: A Potential Microbiome‐Targeted Intervention for Healthy Aging in Rats
Molecular Nutrition &Food Research, EarlyView.Grape seed proanthocyanidin extract (GSPE) promotes a healthier gut phenotype in aged rats. Aging alters gut microbiota composition, increases inflammation, and compromises intestinal barrier function. This study shows that short‐term GSPE treatment in aged rats partially restores microbial diversity toward a youthful profile, modulates mucus‐related ...
Marta Sierra‐Cruz +10 more
wiley +1 more source
Concerning a Case of Invagination of the Ileum Cured by Resection [PDF]
, 1911 Haagn
openalex +1 more source
Molecular Nutrition &Food Research, EarlyView.This work showed that the GLP‐1 response to a meal enriched with oyster mushroom powder in adults with impaired glucose tolerance is modulated by the gut microbiome. Higher GLP‐1 responses following the enriched meal were associated with lower microbial evenness and a microbiome more specialized in fiber degradation.
Linda Klümpen +7 more
wiley +1 more source
Inhibition of the peristaltic reflex of the isolated guinea‐pig ileum
, 1957 H. W. Kosterlitz, Judith A. Robinson
openalex +1 more source
FECAL IMPACTION IN THE ILEUM FOR FIFTY-THREE DAYS, WITH RECOVERY [PDF]
, 1913 ROWLAND H. HARRIS
openalex +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño +4 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Despite predicting poor functional outcomes and being a significant patient burden, there are no approved pharmacotherapies to treat symptoms of cognitive impairment associated with schizophrenia (CIAS). Iclepertin (BI 425809) is a potent and selective inhibitor of glycine transporter‐1 (GlyT1) that was in Phase III development for the ...
Elin M. Matsson +3 more
wiley +1 more source
Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study
Rheumatology &Autoimmunity, EarlyView.This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng +7 more
wiley +1 more source
Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Small Methods, EarlyView.Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz +5 more
wiley +1 more source