Results 21 to 30 of about 248,447 (288)

The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine [PDF]

, 2014
Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT. Objectives:
Bianchi C, Broad RM, Buchheit KH, Budhoo MR, Carter D, Costall B, Costa M, Craig DA, D'Amato M, Eglen RM, Engel G, Erspamer V, Feldberg W, Gale JD, Gebauer A, Gershon MD, Gozlan H, Hedge SS, Hume SP, Humphrey PP, Ivancheva C, Javid FA, Kilbinger H, Kuemmerle JF, Leysen JE, Malleron JL, Mawe GM, Nowak TV, Pan H, Racke K, Radomirov R, Satoh Y, Weber LJ, Yamamoto I   +33 more
core   +1 more source

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease

Frontiers in Immunology, 2020
The Paneth cells reside in the small intestine at the bottom of the crypts of Lieberkühn, intermingled with stem cells, and provide a niche for their neighbors by secreting growth and Wnt-factors as well as different antimicrobial peptides including ...
Jan Wehkamp, Eduard F. Stange
doaj   +1 more source

Altered mucosa-associated microbiota in the ileum and colon of neonatal calves in response to delayed first colostrum feeding.

Journal of Dairy Science, 2019
The present study investigated whether delaying the first feeding of colostrum affected ileum and colon mucosa-associated microbiota in calves. Twenty-seven male Holstein calves were randomly assigned to 1 of 3 groups, fed colostrum at 45 min, 6 h, and ...
T. Ma, E. O’Hara, Yang Song, A. Fischer, Zhixiong He, M. Steele, M. Steele, L. Guan   +7 more
semanticscholar   +1 more source

Early Salmonella Typhimurium infection in pigs disrupts Microbiome composition and functionality principally at the ileum mucosa

Scientific Reports, 2018
Salmonella is a major foodborne pathogen which successfully infects animal species for human consumption such as swine. The pathogen has a battery of virulence factors which it uses to colonise and persist within the host.
H. Argüello, J. Estellé, S. Zaldívar-López, Á. Jiménez-Marín, A. Carvajal, M. A. López-Bascón, F. Crispie, O. O’Sullivan, P. Cotter, F. Priego-Capote, L. Morera, J. Garrido   +11 more
semanticscholar   +1 more source

Epigallocatechin Gallate (EGCG) Promotes the Immune Function of Ileum in High Fat Diet Fed Mice by Regulating Gut Microbiome Profiling and Immunoglobulin Production

Frontiers in Nutrition, 2021
This study aimed to investigate the regulatory effect of epigallocatechin gallate (EGCG) on the composition of the gut microbiome, the transcriptomic profiling of ileum, and their interplay in high fat diet (HFD) induced obese mice.
Xiaoxia Liu, Xiaoxia Liu, Ke Zhao, Ke Zhao, Nana Jing, Qingjun Kong, Xingbin Yang   +6 more
doaj   +1 more source

Dietary High Zinc Oxide Modulates the Microbiome of Ileum and Colon in Weaned Piglets

Frontiers in Microbiology, 2017
Dietary zinc oxide (ZnO) at pharmacological level has been widely used to prevent and treat diarrhea in weaning piglets. Despite its importance for promoting animal health and performance, the influence of microbiome profiles in intestinal tracts by ZnO ...
Ting Yu, Cui Zhu, Shicheng Chen, Lei Gao, Hang Lv, Ruowei Feng, Qingfeng Zhu, Jinsong Xu, Zhuang Chen, Zong-yong Jiang   +9 more
semanticscholar   +1 more source

Switching from a protease inhibitor-based regimen to a dolutegravir-based regimen : a randomized clinical trial to determine the effect on peripheral blood and ileum biopsies from antiretroviral therapy-suppressed human immunodeficiency virus-infected individuals [PDF]

, 2018
Background: Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted ...
Blanco, Julià, Crespo, Manel, De Clercq, Laura, Gálvez, Cristina, Jimenez, Montse, Martinez-Picado, Javier, Moron-Lopez, Sara, Navarro, Jordi, Puertas, Maria C, Ribas, Bibiana Planas, Rutsaert, Sofie, Salgado, Maria, Torrella, Ariadna, Universitat Autònoma de Barcelona, Urrea, Víctor, Vandekerckhove, Linos   +15 more
core   +3 more sources

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. [PDF]

, 2016
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed.
Cai, Linbi, Chen, Zishuo, Duan, Zhongping, Han, Yuan-Ping, Hu, Richard, Lai, Yuchen, Liu, Zhenqui, Lugea, Aurelia, Luo, Mei, Nie, Yuanyang, Pandol, Stephen J, Su, Danmei, Sun, Qun, Tsukamoto, Hidekazu, Wu, Guihui, Wu, Pengfei, Xiao, Zhixiong, Zhang, Li, Zheng, Sujun, Zhu, Airu   +19 more
core   +2 more sources

Retrospective analysis of cases of intestinal invagination treated and followed-up at our clinic

İstanbul Kuzey Klinikleri, 2017
INTRODUCTION[|]The purpose of this study is to present our experience of diagnosis, treatment, clinical course and outcome in invagination.[¤]METHODS[|]Eleven patients; treated due to invagination in ours center between June 2009-July 2015, analyzed ...
Bora Barut, Hüseyin Yönder, Kemal Barış Sarıcı, Fatih Özdemir, Volkan İnce   +4 more
doaj   +1 more source

HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system [PDF]

, 2016
The loss of gut epithelium integrity leads to translocation of microbes and microbial products resulting in immune activation and drives systemic inflammation in acquired immunodeficiency syndrome (AIDS) patients. Although viral loads in HIV patients are
Akbarali, Hamid I., Bhave, Sukhada, Brun, Paola, Dewey, William L., Fitting, Sylvia, Guedia, Joy, Hauser, Kurt F., Kang, Minho   +7 more
core   +1 more source