Results 71 to 80 of about 203,883 (351)
Unique Contractile and Structural Protein Expression in Dog Ileal Inner Circular Smooth Muscle [PDF]
, 2009 This study was designed to test the hypothesis that there is heterogeneous expression of contractile and structural proteins between the smooth muscle cells (SMCs) in the inner and outer circular muscle (ICM and OCM) layers of the ileum ...
Eddinger, Thomas J.
core +1 more source
Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats [PDF]
, 2014 We thank Donna Wallace and the Rowett Animal House staff for the daily care of experimental rats, body weight and food intake measurements and MRI scanning, Vivien Buchan and Donna Henderson of the Rowett Analytical Department for proximate analyses and ...
Adam, Clare L +7 more
core +2 more sources
Advanced Science, EarlyView.DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang +9 more
wiley +1 more source
A Relation-Centric Query Engine for the Foundational Model of Anatomy [PDF]
, 2004 The Foundational Model of Anatomy (FMA), a detailed representation of the structural organization of the human body, was constructed to support the development of software applications requiring knowledge of anatomy.
Ann Li +9 more
core +4 more sources
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
Advanced Science, EarlyView.This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
Diagnostics of dairy and beef cattle diarrhea. [PDF]
, 2012 Calf diarrhea is a multifactorial disease related to a combination of host and pathogen factors. The most common pathogens found in diarrheic calves are cryptosporidium, rotavirus, coronavirus, Salmonella, attaching and effacing E coli and F5 (K99 ...
Blanchard, Patricia Carey
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Ileal ulcer in asymptomatic individuals. Is this Crohn?
Journal of Coloproctology, 2012 The endoscopic finding of ileal ulcers, alone or in small number, is not usual, but when it occurs in asymptomatic patients, an impasse may be generated regarding the action to be taken, since the medical literature is unclear as to how to proceed in ...
Carlos Henrique Marques dos Santos
doaj +1 more source
OncoImmunology, 2020 Why PD-1 blockade is ineffective in the vast majority of colorectal cancers (CCs) lacking microsatellite instability but harboring high densities of tumor infiltrating T cells and follicular T helper (TFH) and B cells remained so far an open conundrum ...
Maria Paula Roberti +3 more
doaj +1 more source
TSE pathogenesis in cattle and sheep [PDF]
, 2008 Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A. +2 more
core +3 more sources