Results 81 to 90 of about 191,017 (312)

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]

open access: yes, 2010
The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell   +12 more
core   +2 more sources

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

open access: yesAdvanced Science, EarlyView.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao   +8 more
wiley   +1 more source

Marmin of Aegle Marmelos Correa Antagonizes AChM3 Receptors: In Silico and In Vitro Studies on IsolatedGuinea Pig Illeum Smooth Muscle

open access: yesJournal of Mathematical and Fundamental Sciences, 2014
A previous study has shown that ethanolic extract of leaves of A. marmelos Correa on isolated ileum had an antagonistic effect on the contraction induced by histamine.
Puguh Noviarsito   +2 more
doaj   +1 more source

Epigenetic silencing of SOCS3 expression contributes to fibrosis in Crohn’s disease [PDF]

open access: yes, 2017
Identified risk polymorphisms affecting the Jak-STAT3 pathway in patients with Crohn’s disease could affect TGF-β1 and collagen I expression and in the pathway’s negative regulator, SOCS3.
Kuemmerle, John F   +2 more
core   +1 more source

Testing the efficacy of medium chain fatty acids against rabbit colibacillosis [PDF]

open access: yes, 2008
Enteropathogenic Escherichia coli (EPEC) represents a major cause of lethal diarrhea in young mammals. Although the pathogenicity mechanisms of EPEC are now well understood, the intrinsic and environmental factors that control the expression of EPEC ...
Alain Milon   +32 more
core   +3 more sources

Preoperative Computed Tomography Colonography‐Angiography for Vascular Mapping to Guide and Standardize D3 Lymphadenectomy in Right‐Sided and Transverse Colon Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study utilized high‐resolution CT colonography‐angiography to systematically classify vascular branching patterns in 591 patients. We defined four reproducible anatomical patterns each for right hemicolectomy and transverse colectomy, demonstrating that an independent‐origin middle colic artery consistently predicts shorter dissection distances ...
Takeharu Kato   +8 more
wiley   +1 more source

Energy Homeostasis of the Artificial Bladder in Experimental Conditions [PDF]

open access: yes, 2018
Patients with Malignant neoplasms of the bladder or severe anatomical and functional bladder abnormalities are the candidates for cystectomy and orthotopic urine diversion.
Dekhtiar, Y. (Yriy)   +3 more
core  

A microscopically assisted limited colectomy mouse model of early colon cancer

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Establishment, surgery, and evaluation process of a microscope‐assisted limited colon resection mouse model for early‐stage colon cancer. Abstract Background Currently, there is a lack of an adequate rodent model for investigating surgical techniques and comprehensive treatment options for patients with colorectal cancer (CRC).
Yu Han   +3 more
wiley   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

open access: yesAnimal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao   +6 more
wiley   +1 more source

Quinine blocks 5-HT and 5-HT3 receptor mediated peristalsis in both guinea pig and mouse ileum tissue [PDF]

open access: yes, 2011
Introduction. Quinine is commonly used to treat malaria; however one of the principal side effects is gastrointestinal disturbances (White, 1992). 5-HT3 receptors modulate gut peristalsis (Chetty et al., 2006), and, as quinine has been shown to act as a ...
Barrett, Iain D.   +4 more
core  

Home - About - Disclaimer - Privacy