Results 211 to 220 of about 16,984 (236)

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

open access: yesAdvanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao   +11 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

open access: yesAdvanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du   +9 more
wiley   +1 more source

Conformal Reconfigurable Intelligent Surfaces: A Cylindrical Geometry Perspective

open access: yesAdvanced Electronic Materials, EarlyView.
Cylindrical reconfigurable intelligent surfaces are explored for low‐complexity beam steering using one‐bit meta‐atoms. A multi‐level modeling approach, including optimization‐based synthesis, demonstrates that even minimal hardware can support directive scattering.
Filippo Pepe   +4 more
wiley   +1 more source

A Compact Hollow Fiber Electrode Assembly Architecture for Continuous Electrochemical Marine Carbon Dioxide Removal

open access: yesAdvanced Energy Materials, EarlyView.
A coaxial, membrane‐integrated hollow fiber electrode assembly (HFEA) is developed for continuous marine carbon mineralization. By utilizing a sub‐millimeter inter‐electrode gap, the HFEA minimizes Ohmic losses, achieving 50% energy reduction and over 85% DIC removal.
Inhwan Park   +5 more
wiley   +1 more source
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The Role of Occupational Therapy with Homeless or Ill-Housed Persons: Perception and Understanding of Occupational Therapy Among Parents and Staff at the Atlanta Children's Day Shelter

Background: People experiencing homelessness oftentimes face barriers that those who are not homeless rarely do. These barriers can range from having limited access to healthy foods and proper healthcare but can also entail experiencing mental illness and substance abuse disorders more frequently than people who have stable housing.
openaire   +1 more source

Traumatic brain injury in precariously housed persons: Incidence and risks

EClinicalMedicine, 2022
William J Panenka   +2 more
exaly  

Using serial position effects to investigate memory dysfunction in homeless and precariously housed persons

Clinical Neuropsychologist, 2023
Kristina M Gicas   +2 more
exaly  

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