Results 21 to 30 of about 125,494 (213)

Snapshot of Permanent Supportive Housing in Illinois [PDF]

open access: yes, 2005
This snapshot report paints the picture of supportive housing in this state, including how much there is, where it is located, whom it serves, how it helps chronically homeless and other at-risk populations become stably housed, and how close it comes to

core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Death Row Conditions Through an Environmental Justice Lens [PDF]

open access: yes, 2017
Glenn Ford lived on death row at Louisiana State Penitentiary for twenty-nine years, three months and five days. Typically, he was confined in his cell for at least twenty-three hours of a given day, seven days a week.
Armstrong, Andrea C.
core   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Demographics of Homelessness Series: The Rising Elderly Population [PDF]

open access: yes, 2010
There is some troubling evidence that homelessness is beginning to increase among elderly adults. In addition, there are demographic factors -- such as the anticipated growth of the elderly population as baby boomers turn 65 years of age and recent ...

core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Welcoming and bonding in nursing care for homeless women in Primary Care

open access: yesRevista Brasileira de Enfermagem
Objectives: to understand primary care nurses’ perceptions regarding the welcoming and building of bonds with homeless women. Methods: a descriptive, qualitative study, conducted with 17 nurses working in primary care in a large city in the countryside ...
Nayara Gonçalves Barbosa   +7 more
doaj   +2 more sources

Homelessness and Substance Abuse: Is Mandatory Treatment the Solution? [PDF]

open access: yes, 1994
For the government to be successful in addressing homelessness, it must focus on the link between homelessness and substance abuse. In New York City and elsewhere, advocates are reluctant to publicize the connection between substance abuse and ...
Abbott, Melanie B.
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Implementing a hospital-based case management intervention for people experiencing homelessness: the navigator program

open access: yesBMC Health Services Research
Background People experiencing homelessness (PEH) have worse health than the general population, and higher rates of hospitalization. The transition period after discharge from hospital is often challenging for PEH, in part due to loss to follow-up ...
Jesse I. R. Jenkinson   +5 more
doaj   +1 more source

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