Results 31 to 40 of about 16,984 (236)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Revista Latino-Americana de EnfermagemObjective: to map the literature on the use of Rapid Molecular Tests in the diagnosis of tuberculosis in people experiencing homelessness. Method: this is a scoping review guided by the Joanna Briggs Institute and the Preferred Reporting Items for ...
Ana Beatriz Marques Valença +5 more
doaj +3 more sources
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
BMC Health Services ResearchBackground People experiencing homelessness (PEH) have worse health than the general population, and higher rates of hospitalization. The transition period after discharge from hospital is often challenging for PEH, in part due to loss to follow-up ...
Jesse I. R. Jenkinson +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Psychological Features of Somatically Ill Persons with Musculoskeletal Disorders
, 2021 В магістерському дослідженні охарактеризовано теоретичні підходи щодо проблеми психологічної адаптації до хронічного захворювання. Проаналізовані загальні індивідуально-психологічні особливості соматично хворих осіб з різними соматичними захворюваннями ...
Bukholdin Mykhailo Yevhenovych +1 more
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Welcoming and bonding in nursing care for homeless women in Primary Care
Revista Brasileira de EnfermagemObjectives: to understand primary care nurses’ perceptions regarding the welcoming and building of bonds with homeless women. Methods: a descriptive, qualitative study, conducted with 17 nurses working in primary care in a large city in the countryside ...
Nayara Gonçalves Barbosa +7 more
doaj +2 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
BMC Public HealthBackground Homelessness among people who inject drugs (PWID) represents a significant and complex public health challenge. However, few studies have investigated the factors contributing to its prevalence, particularly in the Middle East and North Africa
Seyed Aria Nejadghaderi +12 more
doaj +1 more source