Results 241 to 250 of about 700,365 (275)

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

Advanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Yao Chen, Shirui Li, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, Zhongming Liang, Xinlong Jiang, Xiaodong Yang, Pengfei Wang, Ge Yang, Hongmei Wang, Xuezhi Wang, Ming‐Han Tong, Yuanchun Zhou, Shihua Zhang, Yiqiang Chen, Yong Wang, Xin Li   +27 more
wiley   +1 more source

Integrated Cross-Platform Analysis Reveals Candidate Variants and Linkage Disequilibrium-Defined Loci Associated with Osteoporosis in Korean Postmenopausal Women. [PDF]

Diagnostics (Basel)
Kim SK, Hong SJ, Song SI, Lee JK, Kim G, Choi BJ, Seon S, Kim SJ, Ban JY, Kang SW.   +9 more
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Improved genome assembly of Onygena corvina, a keratin-degrading fungus. [PDF]

BMC Res Notes
Pavale S, Eijsink VGH, La Rosa SL.
europepmc   +1 more source

A comparison of short- and long-read whole-genome sequencing for microbial pathogen epidemiology. [PDF]

mSystems
Schiffer AM, Rahman A, Sutton W, Putnam ML, Weisberg AJ.   +4 more
europepmc   +1 more source

AmpWrap: a one-line fully automated amplicon metabarcoding 16S and 18S rRNA gene analysis. [PDF]

Bioinform Adv
Doni L, Marotta A, Vezzulli L, Bosi E.
europepmc   +1 more source

Complete genomes of Rickettsia typhi reveal a clonal population. [PDF]

PLoS Negl Trop Dis
Keeratipusana C, Phuklia W, Phommadeechack V, Thaipadungpanit J, Chansamouth V, Phommasone K, Rattanavong S, Moore CE, Robinson MT, Richards AL, Newton PN, Batty EM.   +11 more
europepmc   +1 more source

High-quality chromosome-level genome assembly of the snake Pseudoxenodon stejnegeri (Squamata: Colubridae). [PDF]

Sci Data
Du L, Chen J, Liu Q, Tan S, Guo P.
europepmc   +1 more source

Illumina/Grail: flawed originalism and the judicial hunch

Journal of Antitrust Enforcement
openaire   +1 more source

A chromosome-level reference genome of the surf parrotfish (Scarus rivulatus). [PDF]

Sci Data
Liang Y, Pan J, Xian L, Zhu K, Guo H, Liu B, Zhang N, Zhang D.   +7 more
europepmc   +1 more source