Results 61 to 70 of about 677,734 (335)
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
A Look at Matisse Methods in Poetry Illustration [PDF]
پیکره, 2012 This article introduces and studies a different aspect of the works of a twen-tieth century artist called Henry Matisse. In addition to the special status of Matisse in twentieth century paintings, he had accepted many book illustra-tions which were ...
Hojatallah Saadatfar
doaj +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
A Study of Implementation Methods in Title Sequence and the Ways it Relates to its Respective Movie [PDF]
پیکره, 2013 As important as it may seem’ categorizing title sequences based on their technique and relation to their respective movies is not paid enough attention yet.
Kian Ashrafi
doaj +1 more source
DRAW: Deep networks for Recognizing styles of Artists Who illustrate children's books [PDF]
arXiv, 2017 This paper is motivated from a young boy's capability to recognize an illustrator's style in a totally different context. In the book "We are All Born Free" [1], composed of selected rights from the Universal Declaration of Human Rights interpreted by different illustrators, the boy was surprised to see a picture similar to the ones in the "Winnie the ...
arxiv
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
, 2016 Growing interest in book and publishing history and the mass digitization of Victorian periodicals and newspapers has given increasing scholarly significance to the study of book and magazine illustration. While some print forms in the 19th century, notably books aimed at children, comic and satirical magazines and serialized fiction, were heavily ...
+8 more sources
Exploring the image of angels in painting of Qajar period [PDF]
پیکره, 2014 The good and evil issues have always busied the human's mind. The image of angels as the most important symbol of goodness has many applications in the literature on the mythologic, epic, religious and vulgar subjects before and after Islam.
Naghmeh Safarzadeh, Bahram Ahmadi
doaj +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source