Results 71 to 80 of about 354,551 (319)

Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma

Frontiers in Oncology, 2021
Adaptive MR-guided radiotherapy (MRgRT) is a new treatment paradigm and its role as a non-invasive treatment option for renal cell carcinoma is evolving.
Brian Keller, Anna M. E. Bruynzeel, Chad Tang, Anand Swaminath, Linda Kerkmeijer, William Chu   +5 more
doaj   +1 more source

Validating Dose Uncertainty Estimates Produced by AUTODIRECT: An Automated Program to Evaluate Deformable Image Registration Accuracy. [PDF]

, 2017
Deformable image registration is a powerful tool for mapping information, such as radiation therapy dose calculations, from one computed tomography image to another. However, deformable image registration is susceptible to mapping errors.
Chen, Josephine, Kim, Hojin, Kirby, Neil, Phillips, Justin, Pukala, Jason, Yom, Sue S   +5 more
core   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Treatment of osteolytic solitary painful osseous metastases with radiofrequency ablation or cryoablation: a retrospective study by propensity analysis [PDF]

, 2016
The present study aimed to measure the improvement in pain relief and quality of life in patients with osteolytic solitary painful bone metastasis treated by cryoablation (CA) or radiofrequency ablation (RFA).
Bonfili, Pierluigi, DI Cesare, Ernesto, DI Staso, Mario, Franzese, Pietro, GRAVINA, GIOVANNI LUCA, Gregori, Lorenzo, Marampon, Francesco, Masciocchi, Carlo, TOMBOLINI, Vincenzo, Zugaro, Luigi   +9 more
core   +2 more sources

Effectiveness of image‐guided radiotherapy for locally advanced esophageal squamous cell carcinoma patients treated with definitive concurrent chemoradiotherapy

Thoracic Cancer, 2019
Image‐guided radiotherapy (IGRT) is an advanced radiotherapy technique to improve the accuracy of treatment delivery. However, a recent randomized controlled trial (RCT) for prostate cancer patients treated with radiotherapy either via IGRT or routine ...
Yao‐Hung Kuo, H. Fang, Yu-sen Lin, M. Lein, Chi‐Ying Yang, S. Ho, Chia-Chin Li, C. Chien   +7 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Mechanical high-intensity focused ultrasound creates unique tumor debris enhancing dendritic cell-induced T cell activation

Frontiers in Immunology, 2022
IntroductionIn situ tumor ablation releases a unique repertoire of antigens from a heterogeneous population of tumor cells. High-intensity focused ultrasound (HIFU) is a completely noninvasive ablation therapy that can be used to ablate tumors either by ...
Renske J. E. van den Bijgaart, Vera E. Mekers, Fabian Schuurmans, Tonke K. Raaijmakers, Melissa Wassink, Andor Veltien, Erik Dumont, Arend Heerschap, Jurgen J. Fütterer, Jurgen J. Fütterer, Gosse J. Adema   +10 more
doaj   +1 more source

Imaging dose and secondary cancer risk in image-guided radiotherapy of pediatric patients

Radiation Oncology, 2018
Daily image-guided radiotherapy (IGRT) can contribute to cover extended body volumes with low radiation dose. The effect of additional imaging dose on secondary cancer development is modelled for a collective of children with Morbus Hodgkin.
Y. Dzierma, Katharina Mikulla, Patrick Richter, K. Bell, P. Melchior, F. Nuesken, C. Rübe   +6 more
semanticscholar   +1 more source

Boron Neutron Capture Therapy Followed by Image-Guided Intensity-Modulated Radiotherapy for Locally Recurrent Head and Neck Cancer: A Prospective Phase I/II Trial

Cancers, 2023
Simple Summary Boron neutron capture therapy (BNCT) is a target radiotherapy and image-guided intensity-modulated radiotherapy (IG-IMRT) that has been used for recurrent head and neck cancer.
Ling-Wei Wang, Y. Liu, P. Chu, Hong-ming Liu, J. Peir, Ko‐Han Lin, Wen-sheng Huang, W. Lo, Jia-Cheng Lee, Tzung-Yi Lin, Yu-Ming Liu, S. Yen   +11 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source