Results 141 to 150 of about 1,186,551 (242)
DeSmoke-LAP: improved unpaired image-to-image translation for desmoking in laparoscopic surgery. [PDF]
Int J Comput Assist Radiol Surg, 2022 Pan Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Image-to-Image Translation for Simplified MRI Muscle Segmentation. [PDF]
Front Radiol, 2021 Gadermayr M +7 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
[Sinogram interpolation combined with unsupervised image-to-image translation network for CT metal artifact correction]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Yu J +5 more
europepmc +1 more source
Image-to-image domain translation using CycleGAN
, 2022 [CA] Els últims avanços enelcampdelesxarxesneuronalshanportatal’augedelesxarxes generatives, les quals necessiten grans quantitats de dades per a entrenar-se. Aquestes dades moltes vegades existeixen en formats que no s’ajusten als requisits dels models d’aprenentatge supervisat.
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Adaptive Contrast Enhancement for Digital Radiographic Images using Image-to-Image Translation
Current Directions in Biomedical EngineeringDigital radiography in medicine is a widely used imaging method for obtaining visual information about the inside of a body. To prepare the acquired raw image for diagnostic evaluation, the contrast must be adjusted depending on the examined part of the ...
Popp Ann-Kathrin +2 more
doaj +1 more source