Results 121 to 130 of about 6,675,235 (374)
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Enhancing Image Annotation With Object Tracking and Image Retrieval: A Systematic Review
Effective image and video annotation is a fundamental pillar in computer vision and artificial intelligence, crucial for the development of accurate machine learning models.
Rodrigo Fernandes +5 more
doaj +1 more source
Ratsnake: A Versatile Image Annotation Tool with Application to Computer-Aided Diagnosis
Image segmentation and annotation are key components of image-based medical computer-aided diagnosis (CAD) systems. In this paper we present Ratsnake, a publicly available generic image annotation tool providing annotation efficiency, semantic awareness,
D. K. Iakovidis +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cograph Regularized Collective Nonnegative Matrix Factorization for Multilabel Image Annotation
Automatic image annotation is an effective and straightforward way to facilitate many applications in computer vision. However, manually annotating images is a computation-expensive and labor-intensive task. To address these problems, this paper proposes
Juli Zhang +3 more
doaj +1 more source
Positive-unlabeled learning for binary and multi-class cell detection in histopathology images with incomplete annotations [PDF]
Zipei Zhao +4 more
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Automatic Creation and Annotation of RGB-D Images for Training Machine Vision Systems
Андрей Жданов +2 more
openalex +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

