Results 91 to 100 of about 21,589 (305)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A robust NIfTI image authentication framework to ensure reliable and safe diagnosis. [PDF]

open access: yesPeerJ Comput Sci, 2023
Basheer S   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Medical Image Authentication Method Based on the Wavelet Packet and Energy Entropy. [PDF]

open access: yesEntropy (Basel), 2022
Sun T   +7 more
europepmc   +1 more source

Semi-fragile watermarking based content image authentication scheme

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2013
This paper presents a block-wise semi-fragile watermarking scheme for image content authentication, with tamper area localization and recovery capability.
Clara Cruz   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

2D Barcodes as Watermarks in Image Authentication

open access: yes6th IEEE/ACIS International Conference on Computer and Information Science (ICIS 2007), 2007
2D barcodes are increasingly used as tags in every type of goods for unique identification. Compared with the 1D barcodes, 2D barcodes not only can carry more data but also can withstand errors in subsequent scans. This property has significant parallels to watermarking logos as such watermarks will withstand multiple manipulations that are common with
Prashan Premaratne, Farzad Safaei
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A Content-based Image Authentication Scheme Based on Singular Value Decomposition

open access: yes, 2009
[[abstract]]In this paper, we propose an image authentication scheme in which image features are embedded for copyright protection and content-tampering detection. The features are based on the invariance of the relationship among SVD coefficients.
Lu, T. C. ; Chang, C.C. ; Liu, Y. L.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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