Results 171 to 180 of about 242,521 (294)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

The development of generative Bayesian models for classification of cell images

open access: yes, 2010
A generative model for shape recognition of biological cells in images is developed. The model is designed for analysing high throughput screens, and is tested on a genome wide morphology screen.
El-Shanawany, A.
core  

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Blu-ray cytometer

open access: yes, 2012
The flow cytometers are one of the most powerful devices used to measure the properties of individual particles passing through a sensing region. In this thesis, a low cost cytometer using a Blu-ray pickup is analysed and further developed. This includes
Albugami, Naser
core  

New Antifungal Susceptibility Test Based on Chitin Detection by Image Cytometry. [PDF]

open access: yesAntimicrob Agents Chemother, 2019
Wang Y   +6 more
europepmc   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

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