Results 221 to 230 of about 285,255 (319)

histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data. [PDF]

Nat Methods, 2017
Schapiro D, Jackson HW, Raghuraman S, Fischer JR, Zanotelli VRT, Schulz D, Giesen C, Catena R, Varga Z, Bodenmiller B.   +9 more
europepmc   +1 more source

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

Advanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing, Ke Jiang, Hua Jiang, Yaru Zhao, Chu‐Hu Lai, Alexandra Aicher, Zonghai Li, Christopher Heeschen   +7 more
wiley   +1 more source

Tracking expression and subcellular localization of RNA and protein species using high-throughput single cell imaging flow cytometry [PDF]

, 2012
Sumit Borah, Lisa Nichols, Lynn M. Hassman, Dean H. Kedes, Joan A. Steitz   +4 more
openalex   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Probing bacterial cell biology using image cytometry. [PDF]

Mol Microbiol, 2017
Cass JA, Stylianidou S, Kuwada NJ, Traxler B, Wiggins PA.   +4 more
europepmc   +1 more source

Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability

Advanced Healthcare Materials, EarlyView.
For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee, Dahae Kim, Taihyun Kim, Chae‐Won Moon, Hyungseok Yong, Sung‐eun Heo, Bumgyu Choi, Yoogyeong Oh, Woojin Choi, Kyungtae Park, Sang‐Jun Ha, Jinkee Hong   +11 more
wiley   +1 more source

BlobFinder, a tool for fluorescence microscopy image cytometry

, 2008
Amin Allalou, Carolina Wählby
openalex   +2 more sources

Analysis of DNA-Guided Self-Assembly of Microspheres Using Imaging Flow Cytometry [PDF]

, 2012
Hao Tang, Ryan Deschner, Peter B. Allen, Younjin Cho, Patrick Sermas, Alejandro Maurer, Andrew D. Ellington, C. Grant Willson   +7 more
openalex   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Streamlining volumetric multi-channel image cytometry using hue-saturation-brightness-based surface creation. [PDF]

Commun Biol, 2018
Tan Y, Li JLY, Goh CC, Lee BTK, Kwok IWH, Ng WJ, Evrard M, Poidinger M, Tey HL, Ng LG.   +9 more
europepmc   +1 more source