Results 81 to 90 of about 948,954 (331)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis

Advanced Science
The liver harbors complex cross‐scale structures, and the fibrosis‐related alterations to these structures have a severe impact on the diverse function of the liver. However, the hepatic anatomic structures and their pathological alterations in the whole‐
Xiaochuan Zhang, Weicheng Yang, Xiaoliang Li, Yanli Zhao, Zongneng Xie, Shuangqu Li, Yue Zeng, Xiaoxu Hao, Xiaohong Xin, Yu Zhang, Zixuan Feng, Hualiang Jiang, Zhaobing Gao, Xianzhen Yin   +13 more
doaj   +1 more source

Image fusion algorithm based on improved K-singular value decomposition and Hadamard measurement matrix

Journal of Algorithms & Computational Technology, 2018
To solve the problem of high time and space complexity of traditional image fusion algorithms, this paper elaborates the framework of image fusion algorithm based on compressive sensing theory.
Qiang Yang, Huajun Wang
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

From Multi-Scale Decomposition to Non-Multi-Scale Decomposition Methods: A Comprehensive Survey of Image Fusion Techniques and Its Applications

IEEE Access, 2017
Image fusion is a well-recognized and a conventional field of image processing. Image fusion provides an efficient way of enhancing and combining pixel-level data resulting in highly informative data for human perception as compared with individual input
Ayush Dogra, Bhawna Goyal, Sunil Agrawal
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Fusion PSPnet Image Segmentation Based Method for Multi-Focus Image Fusion

IEEE Photonics Journal, 2019
To address the problem that the traditional multi-focus images fusion methods cannot fully use of spatial context information. A novel image segmentation method for multi-focus image fusion is proposed.
Jingchun Zhou, Mingliang Hao, Dehuan Zhang, Peiyu Zou, Weishi Zhang   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Critical Review of Multi-focus Image Fusion Based on Deep Learning Method [PDF]

Jisuanji kexue yu tansuo
Multi-focus image fusion is an effective image fusion technology, which aims to combine source images from different focal planes of the same scene to obtain a good fusion result.
LI Ziqi, SU Yuxuan, SUN Jun, ZHANG Yonghong, XIA Qingfeng, YIN Hefeng
doaj   +1 more source