KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Balancing Radiation Dose and Image Quality: Protocol Optimization for Mobile Head CT in Neurointensive Care Unit Patients. [PDF]
Mialkowskyj D +8 more
europepmc +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The impact of off-centered positioning on cone beam CT image quality for image-guided brain SRS treatment. [PDF]
Mail N, Li F, Lalonde R, Huq MS.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Advancing free-breathing liver diffusion-weighted imaging with Propeller-EPI: Improved image quality and ADC repeatability. [PDF]
Liang L +12 more
europepmc +1 more source
Super-Resolution Deep Learning Reconstruction Improves Image Quality of Dynamic Myocardial Computed Tomography Perfusion Imaging. [PDF]
Kobayashi Y +9 more
europepmc +1 more source
Adaptive fusion based deep learning framework for restoring underwater image quality using multi scale attention features. [PDF]
Veeramakali T, Sayeed MS, Yogarayan S.
europepmc +1 more source

