Results 81 to 90 of about 1,174,545 (317)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Topological Image Texture Analysis for Quality Assessment [PDF]

open access: yes, 2017
Image quality is a major factor influencing pattern recognition accuracy and help detect image tampering for forensics. We are concerned with investigating topological image texture analysis techniques to assess different type of degradation.
Aras T. Asaad   +5 more
core   +1 more source

Myocardial involvement characteristics by cardiac MR imaging in neurological and non-neurological Wilson disease patients

open access: yesInsights into Imaging
Objectives To explore the characteristics of myocardial involvement in Wilson Disease (WD) patients by cardiac magnetic resonance (CMR). Methods We prospectively included WD patients and age- and sex-matched healthy population.
Wei Deng   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Image quality optimization, via application of contextual contrast sensitivity and discrimination functions [PDF]

open access: yes, 2015
What is the best luminance contrast weighting-function for image quality optimization? Traditionally measured contrast sensitivity functions (CSFs), have been often used as weighting-functions in image quality and difference metrics. Such weightings have
Fry, E.   +7 more
core   +1 more source

Feasibility and Robustness of 3T Magnetic Resonance Angiography Using Modified Dixon Fat Suppression in Patients With Known or Suspected Peripheral Artery Disease

open access: yesFrontiers in Cardiovascular Medicine, 2020
Objective: Contrast-enhanced magnetic resonance angiography (CE-MRA) is a well-established non-invasive imaging technique for the assessment of peripheral artery disease (PAD). A subtractionless method using modified Dixon (mDixon) fat suppression showed
Karl Jakob Weiss   +16 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Realisation of an Application Specific Multispectral Snapshot-Imaging System Based on Multi-Aperture-Technology and Multispectral Machine Learning Loops

open access: yesSensors
Multispectral imaging (MSI) enables the acquisition of spatial and spectral image-based information in one process. Spectral scene information can be used to determine the characteristics of materials based on reflection or absorption and thus their ...
Lennard Wunsch   +3 more
doaj   +1 more source

Objective measurements of image quality

open access: yesUltrasound in Medicine & Biology, 2004
Tissue harmonic imaging (THI) and compound imaging have been reported clinically to improve contrast resolution, tissue differentiation and overall image quality. However, there have been limited studies to date to quantify objectively the improvements in image quality achieved with these new imaging techniques.
Browne, Jacinta   +4 more
openaire   +5 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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