Results 91 to 100 of about 11,800,567 (295)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Compressed sensing image restoration algorithm based on improved SURF operator

open access: yesOpen Physics, 2018
Aiming at the excellent descriptive ability of SURF operator for local features of images, except for the shortcoming of global feature description ability, a compressed sensing image restoration algorithm based on improved SURF operator is proposed. The
Zhou Guodong   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Image Restoration Technology Based on Discrete Neural network

open access: yesMATEC Web of Conferences, 2015
With the development of computer science and technology, the development of artificial intelligence advances rapidly in the field of image restoration.
Zhou Duoying
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Hybrid regularization inspired by total variation and deep denoiser prior for image restoration

open access: yesComplex & Intelligent Systems
Image restoration is a fundamental problem in computer vision, with the goal of restoring high-quality images from degraded low-quality observation images. However, the ill-posedness of restoration problem often leads to artifacts in the results.
Hu Liang   +3 more
doaj   +1 more source

The Effects of AI-Driven Face Restoration on Forensic Face Recognition

open access: yesApplied Sciences
In biometric recognition, face recognition is a mature and widely used technique that provides a fast, accurate, and reliable method for human identification.
Mengxuan Yang, Shengnan Li, Jinhua Zeng
doaj   +1 more source

Research on the algorithm of electromagnetic leakage reduction and sequence of image migration feature retrieval

open access: yesEURASIP Journal on Image and Video Processing, 2019
When the computer is working, it will transmit the electromagnetic leakage signal containing the video information and receive and process the electromagnetic leakage signal within a certain distance, which can reproduce the screen information and form ...
Chunwei Miao, Jianlin Hu
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

An In-Depth Survey of Underwater Image Enhancement and Restoration

open access: yesIEEE Access, 2019
Images taken under water usually suffer from the problems of quality degradation, such as low contrast, blurring details, color deviations, non-uniform illumination, etc.
Miao Yang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy