Results 91 to 100 of about 715,312 (261)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Unsupervised Selection of Color Factor Weight and Segmentation Scale Parameter for Successful Segmentation of Urban Land Use/Land Cover [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Image segmentation is a crucial step in object-based image analysis of urban remote sensing data. Its primary goal is to divide a digital image into meaningful objects that are internally homogeneous and clearly distinguishable from neighboring segments.
G. B. Ikokou, K. M. Malale
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

IMAGE SEGMENTATION USING MULTIWAVELET TRANSFORM

Journal of Engineering, 2010
This paper presents region growing image segmentation method which unifies region and boundary information. Several studies shown that segmentation based on image features can improve the accuracy of the interpretation.
Manal Fadel Younis
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Image Segmentation

, 2018
Sylvio Barbon, Ana Paula Ayub da Costa Barbon, N.A. Valous, D.F. Barbin   +3 more
  +8 more sources

Optimization and Benchmarking of Image Segmentation for Improved Landmark Detection in Lower Limb X-Rays and Accurate Coronal Plane Alignment of the Knee Classification

IEEE Access
Recent studies have explored image segmentation for landmark detection in computer vision and medical imaging of the lower limb, showing promising results.
Sebastian Amador Sanchez, Ashkan Zarghami, Philippe van Overschelde, Jef Vandemeulebroucke   +3 more
doaj   +1 more source

Semisupervised Soft Mumford-Shah Model for MRI Brain Image Segmentation

Applied Computational Intelligence and Soft Computing, 2016
One challenge of unsupervised MRI brain image segmentation is the central gray matter due to the faint contrast with respect to the surrounding white matter.
Hong-Yuan Wang, Fuhua Chen
doaj   +1 more source

Integrating Semi-supervised and Supervised Learning Methods for Label Fusion in Multi-Atlas Based Image Segmentation

Frontiers in Neuroinformatics, 2018
A novel label fusion method for multi-atlas based image segmentation method is developed by integrating semi-supervised and supervised machine learning techniques.
Qiang Zheng, Qiang Zheng, Qiang Zheng, Yihong Wu, Yong Fan   +4 more
doaj   +1 more source