Results 71 to 80 of about 335,064 (318)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Image Segmentation Based on Deep Learning:A Survey [PDF]
Jisuanji kexueImage segmentation is a fundamental task in computer vision and its main purpose is to extract meaningful and cohe-rent regions from the image input.Over the years,a wide variety oftechniques have been developed in the field of image segmentation ...
HUANG Wenke, TENG Fei, WANG Zidan, FENG Li
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Color and depth based image segmentation using a game-theoretic approach [PDF]
, 2012 In this thesis a new game theoretic approach to image segmentation is proposed. It is an attempt to give a contribution to a new interesting research area in image processing, which tries to boost image segmentation combining information about ...
Favaro, Martina
core
Facial soft tissue segmentation [PDF]
, 2014 The importance of the face for socio-ecological interaction is the cause for a high demand on any surgical intervention on the facial musculo-skeletal system.
Majeed, Tahir
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A New Nonlinear Diffusion Equation Model for Noisy Image Segmentation
Advances in Mathematical Physics, 2016 Image segmentation and image denoising are two important and fundamental topics in the field of image processing. Geometric active contour model based on level set method can deal with the problem of image segmentation, but it does not consider the ...
Bo Chen +5 more
doaj +1 more source
CoRR, 2017 We propose an automatic algorithm, named SDI, for the segmentation of skin lesions in dermoscopic images, articulated into three main steps: selection of the image ROI, selection of the segmentation band, and segmentation. We present extensive experimental results achieved by the SDI algorithm on the lesion segmentation dataset made available for the ...
Mario Rosario Guarracino +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source