Results 51 to 60 of about 732,251 (333)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Statistical region based active contour using a fractional entropy descriptor: Application to nuclei cell segmentation in confocal microscopy images [PDF]

open access: yes, 2013
We propose an unsupervised statistical region based active contour approach integrating an original fractional entropy measure for image segmentation with a particular application to single channel actin tagged fluorescence confocal microscopy image ...
Carreiras, F   +5 more
core   +1 more source

Automatic Image Segmentation by Dynamic Region Merging

open access: yes, 2010
This paper addresses the automatic image segmentation problem in a region merging style. With an initially over-segmented image, in which the many regions (or super-pixels) with homogeneous color are detected, image segmentation is performed by ...
Peng, Bo, Zhang, David, Zhang, Lei
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

A Survey on Medical Image Segmentation Based on Deep Learning Techniques

open access: yesBig Data and Cognitive Computing, 2022
Deep learning techniques have rapidly become important as a preferred method for evaluating medical image segmentation. This survey analyses different contributions in the deep learning medical field, including the major common issues published in recent
Jayashree Moorthy, Usha Devi Gandhi
doaj   +1 more source

Improved Depth Map Estimation from Stereo Images based on Hybrid Method [PDF]

open access: yes, 2012
In this paper, a stereo matching algorithm based on image segments is presented. We propose the hybrid segmentation algorithm that is based on a combination of the Belief Propagation and Mean Shift algorithms with aim to refine the disparity and depth ...
Breznan, M.   +4 more
core   +1 more source

Automatic Segmentation of Fluorescence Lifetime Microscopy Images of Cells Using Multi-Resolution Community Detection

open access: yes, 2013
We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method.
Dempster   +24 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

An efficient approach for optimal multilevel thresholding selection for gray scale images based on improved differential search algorithm

open access: yesAin Shams Engineering Journal, 2018
Segmentation is one of the important steps for image analysis. Multilevel thresholding image segmentation was more popular in image segmentation. Otsu and Kapur based methods are most popular for multilevel threshold image segmentation.
Sowjanya Kotte   +2 more
doaj   +1 more source

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