Results 151 to 160 of about 630,838 (311)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Automatic segmentation of Caenorhabditis elegans skeletons in worm aggregations using improved U-Net in low-resolution image sequences. [PDF]

Heliyon, 2023
Layana Castro PE, Garví AG, Sánchez-Salmerón AJ.   +2 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Deformable and articulated 3D reconstruction from monocular video sequences

, 2012
PhDThis thesis addresses the problem of deformable and articulated structure from motion from monocular uncalibrated video sequences. Structure from motion is defined as the problem of recovering information about the 3D structure of scenes imaged by a
Paladini, Marco
core  

On robust optical flow estimation on image sequences with differently exposed frames using primal-dual optimization

, 2017
Optical flow methods are used to estimate pixelwise motion information based on consecutive frames in image sequences. The image sequences traditionally contain frames that are similarly exposed. However, many real-world scenes contain high dynamic range
Lindström, Konstantin, Lindström, Konstantin,, McKelvey, Tomas, Bengtsson, Tomas,, Lindstr\uf6m, Konstantin, Bengtsson, Tomas, McKelvey, Tomas,   +6 more
core   +1 more source

Suppression of motion artifacts in intravascular photoacoustic image sequences. [PDF]

Biomed Opt Express, 2021
Sun Z, Du J.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Deep learning-based classification of DSA image sequences of patients with acute ischemic stroke. [PDF]

Int J Comput Assist Radiol Surg, 2022
Mittmann BJ, Braun M, Runck F, Schmitz B, Tran TN, Yamlahi A, Maier-Hein L, Franz AM.   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Investigation of a new method for improving image resolution for camera tracking applications

, 2015
Camera based systems have been a preferred choice in many motion tracking applications due to the ease of installation and the ability to work in unprepared environments.
Longstaff, Andrew P., Fletcher, Simon, Longstaff, Andrew, Alzarok, Hamza, Myers, Alan   +4 more
core